Eğitim Bilgileri
1994 - 2000
1994 - 2000Doktora
Gazi Üniversitesi, Sağlık Bilimleri Enstitüsü, -, Türkiye
1991 - 1994
1991 - 1994Yüksek Lisans
Gazi Üniversitesi, Sağlık Bilimleri Enstitüsü, Türkiye
1986 - 1991
1986 - 1991Lisans
Gazi Üniversitesi, Eczacılık Fakültesi, Türkiye
Yaptığı Tezler
2000
2000Doktora
Bazı 1,2-Disübstitüe Benzimidazol Türevlerinin Platin(II) Kompeksleri Üzerinde Çalışmalar
Erzincan Binali Yıldırım Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
1994
1994Yüksek Lisans
Bazı 5-Sübstitüe-2-Hidroksimetilbenzimidazol Türevlerinin Platin(II) Kompeksleri Üzerinde Çalışmalar
Erzincan Binali Yıldırım Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Yabancı Diller
C1 İleri
C1 İleriİngilizce
Sertifika, Kurs ve Eğitimler
2021
2021Eğiticilerin Eğitimi
Eğitim Yönetimi ve Planlama
Erzincan Binali Yıldırım Üniversitesi
Araştırma Alanları
Farmasötik Kimya
Akademik Ünvanlar / Görevler
2021 - Devam Ediyor
2021 - Devam EdiyorProf. Dr.
Erzincan Binali Yıldırım Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bilimleri Bölümü
Makaleler
Tümü (52)
SCI-E, SSCI, AHCI (49)
SCI-E, SSCI, AHCI, ESCI (51)
ESCI (2)
Scopus (51)
TRDizin (4)
2025
20251. Benzoxazole Derivatives as Dual p38α Mitogen-Activated Protein Kinase and Acetylcholinesterase Inhibitors: Design, Synthesis, and Evaluation for Alzheimer's Disease and Cancer Therapy
Zoatier B., Yildiztekin G., ALAGÖZ M. A., Hepokur C., DİLEK E., Algul O.
ChemMedChem
, cilt.20, sa.22, 2025 (SCI-Expanded, Scopus)
2025
20252. Design, Synthesis, and In Silico Analyses of Nitroimidazole Derivatives Targeting Cholinesterases
Biyik B., Tarıkogulları A. H., ALAGÖZ M. A., Demir Y., GÜLÇİN İ., BURMAOĞLU S., et al.
ChemistrySelect
, cilt.10, sa.35, 2025 (SCI-Expanded, Scopus)
2025
20253. Synthesis and evaluation of sulfonamide-chalcone hybrid compounds as inhibitors of VEGFR1/VEGFR2-mediated angiogenesis
Barlak N., Sanli F., Celik S., İskender B., ANIL D., Gambacorta N., et al.
Bioorganic Chemistry
, cilt.164, 2025 (SCI-Expanded, Scopus)
2025
20254. Development of Potent Type V MAPK Inhibitors: Design, Synthesis, and Biological Evaluation of Benzothiazole Derivatives Targeting p38α MAPK in Breast Cancer Cells.
Zoatier B., Gizem Yildiztekin K. G., Abdullah Alagoz M., Hepokur C., BURMAOĞLU S., Algul O.
Archiv der Pharmazie
, cilt.358, sa.4, 2025 (SCI-Expanded, Scopus)
2025
20255. Pyrrole-Tethered Bisbenzoxazole Derivatives: Apoptosis-Inducing Agents Targeting Breast Cancer Cells
Kuzu B., Yetkin D., Hepokur C., Algul O.
Chemical Biology and Drug Design
, cilt.105, sa.3, 2025 (SCI-Expanded, Scopus)
2025
20256. Structure-based inhibition of acetylcholinesterase and butyrylcholinesterase with 2-Aryl-6-carboxamide benzoxazole derivatives: synthesis, enzymatic assay, and in silico studies
Kuzu B., ALAGÖZ M. A., Demir Y., GÜLÇİN İ., BURMAOĞLU S., Algul O.
Molecular Diversity
, cilt.29, sa.1, ss.671-693, 2025 (SCI-Expanded, Scopus)
2024
20247. Exploring new 5-Nitroimidazole Derivatives as Potent Acetylcholinesterase and Butyrylcholinesterase Enzyme Inhibitors
Gursoy Ş., Satıcı D., Kuzu B., Turkmenoglu B., Dilek E., Algul Ö.
Chemistry and Biodiversity
, cilt.21, sa.10, 2024 (SCI-Expanded, Scopus)
2024
20248. From Deep Learning to the Discovery of Promising VEGFR-2 Inhibitors
YÜCEL M. A., Adal E., Aktekin M. B., Hepokur C., Gambacorta N., Nicolotti O., et al.
ChemMedChem
, cilt.19, sa.16, 2024 (SCI-Expanded, Scopus)
2024
20249. Synthesis and antitubercular activities of acetamide-substituted benzazole derivatives
GÜRSOY Ş., Öztürk E. Ş., Zoatier B., ÜLGER M., ALGÜL Ö.
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
, cilt.17, 2024 (TRDizin)
2024
202410. Investigation of Some Metabolic Enzyme Inhibition Properties of Novel Chalcone-Cu Complexes
Ebiri R., Turgut M., Aktas Anil D., Demir Y., Saglamtas R., Abdullah Alagoz M., et al.
ChemistrySelect
, cilt.9, sa.27, 2024 (SCI-Expanded, Scopus)
2024
202411. Hydrazide-Bridged Pyridazines for Cholinesterase Inhibitors: Synthesis, Characterizations, In Silico, and In Vitro Evaluation
Gürsoy Ş., Taşkor Önel G., Türkmenoğlu B., Bozbey Merde İ., Dilek E., Özsoy C., et al.
CHEMISTRYSELECT
, cilt.9, sa.e202400085, ss.1-12, 2024 (SCI-Expanded, Scopus)
2024
202412. Deep learning approach to the discovery of novel bisbenzazole derivatives for antimicrobial effect
Barcin T., Yücel M. A., Ersan R. H., Alagoz M. A., Dogen A., Burmaoglu S., et al.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1295, ss.136668-136679, 2024 (SCI-Expanded, Scopus)
2024
202413. Assessing the Antiangiogenic Effects of Chalcones and Their Derivatives
BURMAOĞLU S., Gobek A., ANIL D., ALAGÖZ M. A., Guner A., Güler C., et al.
Polycyclic Aromatic Compounds
, cilt.44, sa.1, ss.51-66, 2024 (SCI-Expanded, Scopus)
2023
202314. Machine learning study: from the toxicity studies to tetrahydrocannabinol effects on Parkinson's disease
YÜCEL M. A., Ozcelik İ., ALGÜL Ö.
Future medicinal chemistry
, cilt.15, sa.4, ss.365-377, 2023 (SCI-Expanded, Scopus)
2023
202315. Novel oxalamide derivatives for COXs expression and breast cancer: design, synthesis, biological evaluation, and docking studies
Kuzu B., Hepokur C., Algul O.
Organic Communications
, cilt.16, sa.3, ss.152-165, 2023 (ESCI, Scopus)
2022
202216. 2-Phenyl substituted Benzimidazole derivatives: Design, synthesis, and evaluation of their antiproliferative and antimicrobial activities
Ersan R. H., Kuzu B., Yetkin D., ALAGÖZ M. A., Dogen A., BURMAOĞLU S., et al.
Medicinal Chemistry Research
, cilt.31, sa.7, ss.1192-1208, 2022 (SCI-Expanded, Scopus)
2022
202217. Synthesis, molecular docking and some metabolic enzyme inhibition properties of biphenyl-substituted chalcone derivatives
BURMAOĞLU S., Kazancioglu E. A., Kazancioglu M. Z., Sağlamtaş R., Yalcin G., GÜLÇİN İ., et al.
Journal of Molecular Structure
, cilt.1254, 2022 (SCI-Expanded, Scopus)
2022
202218. Synthesis, Biological Evaluation and In Silico Studies of Some 2-Substituted Benzoxazole Derivatives as Potential Anticancer Agents to Breast Cancer
Kuzu B., Hepokur C., ALAGÖZ M. A., BURMAOĞLU S., Algul O.
ChemistrySelect
, cilt.7, sa.1, 2022 (SCI-Expanded, Scopus)
2022
202219. Synthesis, In Vitro Biological Evaluation, and Molecular Docking Studies of Novel Biphenyl Chalcone Derivatives as Antimicrobial Agents
BURMAOĞLU S., Kazancioglu E. A., Kazancioglu M. Z., ALAGÖZ M. A., Dogen A., Algul Ö.
POLYCYCLIC AROMATIC COMPOUNDS
, cilt.42, sa.9, ss.5948-5961, 2022 (SCI-Expanded, Scopus)
2022
202220. Bisbenzoxazole Derivatives: Design, Synthesis, in Vitro Antimicrobial, Antiproliferative Activity, and Molecular Docking Studies
Ersan R. H., ALAGÖZ M. A., Dogen A., Duran N., BURMAOĞLU S., Algul Ö.
POLYCYCLIC AROMATIC COMPOUNDS
, cilt.42, sa.6, ss.3103-3123, 2022 (SCI-Expanded, Scopus)
2022
202221. Design, synthesis and antiproliferative activity evaluation of fluorine-containing chalcone derivatives
BURMAOĞLU S., ANIL D., Gobek A., KILIÇ D., Yetkin D., Duran N., et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
, cilt.40, sa.8, ss.3525-3550, 2022 (SCI-Expanded, Scopus)
2021
202122. Revisit to the synthesis of 1,2,3,4-tetrasubstituted pyrrole derivatives in lactic acid media as a green solvent and catalyst
AKBAŞLAR D., Giray E. S., Algul Ö.
MOLECULAR DIVERSITY
, cilt.25, sa.4, ss.2321-2338, 2021 (SCI-Expanded, Scopus)
2021
202123. Bisbenzimidazole Derivatives as Potential Antimicrobial Agents: Design, Synthesis, Biological Evaluation and Pharmacophore Analysis
Ersan R. H., BOLELLİ K., Gonca S., Dogen A., BURMAOĞLU S., Algul Ö.
PHARMACEUTICAL CHEMISTRY JOURNAL
, cilt.55, sa.2, ss.149-158, 2021 (SCI-Expanded, Scopus)
2021
202124. Synthesis of Benzoxazole-2-carboxylate Derivatives: Electronic- and Position-effect of Functional Groups and Computational Modeling of the Selectivity for Oxazole Ring
Kuzu B., Sari O., ERDEM S., Algul Ö., Mengeş N.
CHEMISTRYSELECT
, cilt.6, sa.10, ss.2529-2538, 2021 (SCI-Expanded, Scopus)
2021
202125. One-pot synthesis of novel benzimidazoles with a naphthalene moiety as antimicrobial agents and molecular docking studies
Ersan R. H., Yuksel A., Ertan-Bolelli T., Dogen A., BURMAOĞLU S., Algul Ö.
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
, cilt.68, sa.2, ss.374-383, 2021 (SCI-Expanded, Scopus)
2020
202026. Investigation of New Benzimidazole Derivative Compounds' Effects on A549 Cell Line
Duran G. G., Kucuk M. U., Algul Ö., Terzi M. Y.
BRAZILIAN ARCHIVES OF BIOLOGY AND TECHNOLOGY
, cilt.63, 2020 (SCI-Expanded, Scopus)
2019
201927. Synthesis of New Alicyclic Oxalamide Derivatives and Their Differential Immunomodulatory Activities on the Mammalian Cells
Kuzu B., Ayaz F., Algul Ö.
JOURNAL OF HETEROCYCLIC CHEMISTRY
, cilt.56, sa.7, ss.1946-1952, 2019 (SCI-Expanded, Scopus)
2019
201928. Symmetric bis-benzoxazole-based chemicals exerted anti-inflammatory effect on danger signal LPS-stimulated macrophages
Ayaz F., Ersan R. H., Algul Ö.
MONATSHEFTE FUR CHEMIE
, cilt.150, sa.6, ss.1137-1146, 2019 (SCI-Expanded, Scopus)
2019
201929. Immunomodulatory and immunostimulatory effects of some bisbenzoxazole derivatives on lipopolysaccharide stimulated mammalian macrophages
Ayaz F., Isse Q. A., Kheeree R., Ersan R. H., Algul Ö.
JOURNAL OF RESEARCH IN PHARMACY
, cilt.23, sa.5, ss.944-951, 2019 (ESCI, Scopus, TRDizin)
2019
201930. Bisbenzoxazole derivatives had an antiinflammatory effect on in vitro stimulated macrophages
Ayaz F., Kheeree R., Isse Q. A., Ersan R. H., Algul Ö.
TURKISH JOURNAL OF CHEMISTRY
, cilt.43, sa.3, ss.963-977, 2019 (SCI-Expanded, Scopus, TRDizin)
2018
201831. Molecular docking studies on fluoro-substituted chalcones as potential DprE1 enzyme inhibitors
Yalcin G., BURMAOĞLU S., Yildiz I., Algul Ö.
JOURNAL OF MOLECULAR STRUCTURE
, cilt.1164, ss.50-56, 2018 (SCI-Expanded, Scopus)
2018
201832. Synthesis and biological evaluation of phloroglucinol derivatives possessing -glycosidase, acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase inhibitory activity
BURMAOĞLU S., YILMAZ A. B., Taslimi P., Algul Ö., Kilic D., GÜLÇİN İ.
ARCHIV DER PHARMAZIE
, cilt.351, sa.2, 2018 (SCI-Expanded, Scopus)
2017
201733. Design of potent fluoro-1substituted chalcones as antimicrobial agents
Burmaoglu S., Algul Ö., Gobek A., Anil D. A., Ulger M., Erturk B. G., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.32, sa.1, ss.490-495, 2017 (SCI-Expanded, Scopus)
2016
201634. Synthesis and anti-proliferative activity of fluoro-substituted chalcones
Burmaoglu S., ALGUL Ö., ANıL D., GOBEK A., DURAN G., ERSAN R., et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
, cilt.26, sa.13, ss.3172-3176, 2016 (SCI-Expanded, Scopus)
2016
201635. Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines
Kucukoglu K., Oral F., Aydin T., Yamali C., Algul Ö., Sakagami H., et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
, cilt.31, ss.20-24, 2016 (SCI-Expanded, Scopus)
2011
201136. Synthesis and Antifungal Evaluation of 1-Aryl-2-dimethylaminomethyl-2-propen-1-one Hydrochlorides
METE E., GÜL H. İ., Bilginer S., Algul Ö., Topaloglu M. E., GÜLLÜCE M., et al.
MOLECULES
, cilt.16, sa.6, ss.4660-4671, 2011 (SCI-Expanded, Scopus)
2011
201137. 2-(4-Methoxy-2-methylanilino)-1,2-diphenylethanone
Arslan H., Algul Ö., Zirek S., Tari O., Demircan A., Hardcastle K. I.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE
, cilt.67, 2011 (SCI-Expanded, Scopus)
2011
201138. 2,4-Diamino-5-(2 '-arylpropargyl)pyrimidine derivatives as new nonclassical antifolates for human dihydrofolate reductase inhibition
Algul Ö., Paulsen J. L., Anderson A. C.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING
, cilt.29, sa.5, ss.608-613, 2011 (SCI-Expanded, Scopus)
2009
200939. Comparative studies on conventional and microwave-assisted synthesis of a series of 2,4-di and 2,3,4-trisubstituted benzimidazol[1,2-a] pyrimidines and their antimicrobial activities
Algul Ö., Meric A., Polat S., Yuksek N. D., Serin M. S.
CENTRAL EUROPEAN JOURNAL OF CHEMISTRY
, cilt.7, sa.3, ss.337-342, 2009 (SCI-Expanded, Scopus)
2008
200840. Vibrational spectroscopy investigation using ab initio and density functional theory analysis on the structure of 3-(6-benzoyl-2-oxobenzo[d]oxazol-3(2H)-yl)propanoic acid
Arslan H., Algul Ö., Onkol T.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
, cilt.70, sa.3, ss.606-614, 2008 (SCI-Expanded, Scopus)
2008
200841. Vibrational spectrum and assignments of 2-(4-methoxyphenyl)-1 H-benzo[d]imidazole by ab initio Hartree-Fock and density functional methods
Arslan H., Alguel Ö.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
, cilt.70, sa.1, ss.109-116, 2008 (SCI-Expanded, Scopus)
2008
200842. Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17 beta-hydroxysteroid dehydrogenase type 1 (17 beta-HSD1) for the treatment of estrogen-dependent diseases
Bey E., Marchais-Oberwinkler S., Kruchten P., Frotscher M., Werth R., Oster A., et al.
BIOORGANIC & MEDICINAL CHEMISTRY
, cilt.16, sa.12, ss.6423-6435, 2008 (SCI-Expanded, Scopus)
2008
200843. Comparative studies on conventional and microwave synthesis of some benzimidazole, benzothiazole and indole derivatives and testing on inhibition of hyaluronidase
Algul Ö., Kaessler A., Apcin Y., Yilmaz A., Jose J.
MOLECULES
, cilt.13, sa.4, ss.736-748, 2008 (SCI-Expanded, Scopus)
2007
200744. Synthesis and Ab Initio/DFT Studies on 2-(4-methoxyphenyl)benzo[d]thiazole
Arslan H., Alguel Ö.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
, cilt.8, sa.8, ss.760-776, 2007 (SCI-Expanded, Scopus)
2007
200745. Structural and spectral studies on,3-(6-benzoyl-5-chloro-2-benzoxazolinon-3-yl) propanoic acid
Arslan H., Algul Ö., Dundar Y.
VIBRATIONAL SPECTROSCOPY
, cilt.44, sa.2, ss.248-255, 2007 (SCI-Expanded, Scopus)
2007
200746. Synthesis and evaluation of antimicrobial activity of some 1,5(6)-H/or -methyl-2-subtituted benzimidazole derivatives
Algul Ö., Duran N., Gulbol G.
ASIAN JOURNAL OF CHEMISTRY
, cilt.19, sa.4, ss.3085-3092, 2007 (SCI-Expanded, Scopus)
2007
200747. Activity of bisbenzimidazoles derivatives to Staphylococcus epidermidis
Algul Ö., Duran N.
ASIAN JOURNAL OF CHEMISTRY
, cilt.19, sa.4, ss.3145-3151, 2007 (SCI-Expanded, Scopus)
2007
200748. Theoretical studies of molecular structure and vibrational spectra of 2-ethyl-1H-benzo[d]imidazole
Arslan H., Algul Ö.
ASIAN JOURNAL OF CHEMISTRY
, cilt.19, sa.3, ss.2229-2235, 2007 (SCI-Expanded, Scopus)
2007
200749. A microplate based screening of benzimidazole derivatives on hyaluronidase inhibition at PH 7 and 3.5
Kaessler A., Algul Ö., Jose J.
LETTERS IN DRUG DESIGN & DISCOVERY
, cilt.4, sa.8, ss.562-569, 2007 (SCI-Expanded, Scopus)
2005
200550. Synthesis, characterization and genotoxicity of platinum(II) complexes with subtituted benzimidazole ligands
Algul Ö., Ozcelik B., Abbasoglu U., Gumus F.
TURKISH JOURNAL OF CHEMISTRY
, cilt.29, sa.6, ss.607-615, 2005 (SCI-Expanded, Scopus, TRDizin)
2003
200351. Synthesis, cytotoxic activity on MCF-7 cell line and mutagenic activity of platinum(II) complexes with 2-substituted benzimidazole ligands
Gumus F., Algul Ö., EREN G., Eorglu H., Diril N., Gur S., et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
, cilt.38, sa.5, ss.473-480, 2003 (SCI-Expanded, Scopus)
1997
199752. DNA binding studies with cis-dichlorobis (5(6)-non/chlorosubstituted-2-hydroxymethyl-benzimidazole) platinum(II) complexes
Gumus F., Algul Ö.
JOURNAL OF INORGANIC BIOCHEMISTRY
, cilt.68, sa.1, ss.71-74, 1997 (SCI-Expanded, Scopus)
Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler
2024
20241. Synthesis of Chalcone-Pyrrol Hybrid Derivatives and Investigation of Their Antiproliferative Effects
Gürsoy Ş., Yücel M. A., Yıldıztekin K. G., Türkmenoğlu B., Polat M. F., Algül Ö.
12. International Drug Chemistry Conference, Antalya, Türkiye, 7 - 10 Mart 2024, ss.104-108, (Tam Metin Bildiri)
2024
20242. Synthesis of Benzoxazole Derivatives and Investigation of Their mTOR Inhibitor Activities
Çolak S., Gürsoy Ş., Kuzu B., Türkmenoğlu B., Burmaoğlu S., Algül Ö.
12. International Drug Chemistry Conference, Antalya, Türkiye, 7 - 10 Mart 2024, ss.104-108, (Tam Metin Bildiri)
2022
20223. Screening of JAK-2 Inhibitors with Machine Learning
YÜCEL M. A., ALGÜL Ö.
2.Computer-Aided Drug Design Symposium and Workshop, İstanbul, Türkiye, 11 - 12 Mayıs 2022, (Özet Bildiri)
2021
20214. Screening of β2-Receptor Inhibitors with Machine Learning
YÜCEL M. A., ALGÜL Ö.
10. İlaç Kimyası Kongresi, Antalya, Türkiye, 10 Mart 2021, ss.96-99, (Tam Metin Bildiri)