Education
2012 - 2016
2012 - 2016Doctorate
Akdeniz University, Institute Of Science, Gıda Mühendisliği Abd, Turkey
2010 - 2012
2010 - 2012Postgraduate
Akdeniz University, Institute Of Science, Gıda Mühendisliği Abd, Turkey
2005 - 2010
2005 - 2010Undergraduate
Akdeniz University, Faculty Of Engineering, Department Of Food Engineering, Turkey
Dissertations
2016
2016Doctorate
Pichia Pastoris Etanol Metabolizması Üzerine Çalışmalar
Akdeniz University, Faculty Of Engineering, Department Of Food Engineering
2012
2012Postgraduate
Pichia Pastoris Alkol Oksidaz (AOX1 ve AOX2) Genlerinin İnaktif Edilmesi ve Elde Edilen Suşun Rekombinant Protein Üretiminde Kullanılması
Akdeniz University, Faculty Of Engineering, Department Of Food Engineering
Research Areas
Food Engineering
Life Sciences
Biotechnology
Bioreactor
Microbial Biotechnology
Molecular Biology and Genetics
Research Areas Based on Academic Activities
Avesis Research Areas
WoS Research Areas
Scopus Research Areas
Academic Positions
2024 - Continues
2024 - ContinuesAssociate Professor
Erzincan Binali Yildirim University, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü
2018 - Continues
2018 - ContinuesAssistant Professor
Erzincan Binali Yildirim University, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü
2016 - 2018
2016 - 2018Assistant Professor
Erzincan Binali Yildirim University, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü
Managerial Experience
2021 - Continues
2021 - ContinuesUygulama ve Araştırma Merkezi Yönetim Kurulu Üyesi
Erzincan Binali Yildirim University, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü
2021 - Continues
2021 - ContinuesDeputy Head of Department
Erzincan Binali Yildirim University, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü
2021 - Continues
2021 - ContinuesRectorate Commissioner
Erzincan Binali Yildirim University, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü
2020 - Continues
2020 - ContinuesBölüm Akademik Teşvik Değerlendirme Komisyonu Üyesi
Erzincan Binali Yildirim University, Mühendislik-Mimarlık Fakültesi, Gıda Mühendisliği Bölümü
2018 - 2020
2018 - 2020Assistant Director of the Institute
Erzincan Binali Yildirim University, Fen Bilimleri Enstitüsü
Articles
2025
20251. Analysis of possible effects of recombinant antimicrobial peptide TP4 on colon cancer line HT-29
Kılınç S., KARAOĞLAN M., KUZUCU M.
Medical Oncology
, vol.42, no.8, 2025 (SCI-Expanded, Scopus)
2025
20252. Isolation and Characterization of Lytic Bacteriophages Specific to Foodborne Pathogenic Pseudomonas aeruginosa and Use as a Biopreservative in Chicken Meat
YILMAZ N., Yildirim Z., Sahin T. S., KARAOĞLAN M.
Food and Bioprocess Technology
, vol.18, no.3, pp.2545-2560, 2025 (SCI-Expanded, Scopus)
2024
20243. Enhanced Production and Therapeutic Evaluation of TP4 Peptide in Pichia pastoris Against Hepatocellular Carcinoma HUH-7 Cells
KILINÇ S., KARAOĞLAN M., KUZUCU M.
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
, vol.17, pp.505-522, 2024 (TRDizin)
2023
20234. Alternative secretory signal sequences for recombinant protein production in Pichia pastoris
KARAOĞLAN M.
Enzyme and Microbial Technology
, vol.168, 2023 (SCI-Expanded, Scopus)
2023
20235. Improvement of recombinant L-Asparaginase production in Pichia pastoris
ERDEN KARAOĞLAN F., KARAOĞLAN M.
3 Biotech
, vol.13, no.5, 2023 (SCI-Expanded, Scopus)
2022
20226. Bakteriyel Kaynaklı Lipaz Geninin Pichia pastoris’te Klonlanması, Ekspresyonu ve Rekombinant Enzimin Saflaştırılması
Erden Karaoğlan F., Karaoglan M.
Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi
, vol.12, no.4, pp.2209-2222, 2022 (TRDizin)
2022
20227. Applicability of the heterologous yeast promoters for recombinant protein production in Pichia pastoris
Erden Karaoğlan F., Karaoğlan M.
Applied Microbiology and Biotechnology
, vol.106, no.21, pp.7073-7083, 2022 (SCI-Expanded, Scopus)
2022
20228. Deletion analysis of Pichia pastoris alcohol dehydrogenase 2 (ADH2) promoter and development of synthetic promoters.
ERDEN KARAOĞLAN F., KARAOĞLAN M., Yılmaz G., Yılmaz S., İNAN M.
Biotechnology journal
, vol.17, no.2, 2022 (SCI-Expanded, Scopus)
2021
20219. Extracellular Production and Purification of the β-glucanase in Pichia pastoris Expression System
Karaoğlan M., Erden Karaoğlan F.
Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi , vol.14, no.2, pp.620-630, 2021 (TRDizin)
2020
202010. Partial purification and characterization of a recombinant beta-mannanase from Aspergillus fumigatus expressed in Aspergillus sojae grown on carob extract
Karahalil E., Germec M., Karaoğlan M., Yatmaz E., Coban H. B., İnan M., et al.
BIOMASS CONVERSION AND BIOREFINERY
, vol.10, no.4, pp.1189-1205, 2020 (SCI-Expanded, Scopus)
2020
202011. Effect of codon optimization and promoter choice on recombinant endo-polygalacturonase production in Pichia pastoris
KARAOĞLAN M., ERDEN KARAOĞLAN F.
ENZYME AND MICROBIAL TECHNOLOGY
, vol.139, 2020 (SCI-Expanded, Scopus)
2020
202012. Identification of major ADH genes in ethanol metabolism of Pichia pastoris
Karaoglan M., Erden-Karaoglan F., Yilmaz S., İNAN M.
Yeast
, vol.37, no.2, pp.227-236, 2020 (SCI-Expanded, Scopus)
2019
201913. Cloning and expression of pullulanase from Bacillus subtilis BK07 and PY22 in Pichia pastoris
ERDEN KARAOĞLAN F., KARAKAŞ BUDAK B., KARAOĞLAN M., İNAN M.
PROTEIN EXPRESSION AND PURIFICATION
, vol.162, pp.83-88, 2019 (SCI-Expanded, Scopus)
2016
201614. Comparison of ADH3 promoter with commonly used promoters for recombinant protein production in Pichia pastoris
Karaoglan M., Karaoglan F. E., İNAN M.
PROTEIN EXPRESSION AND PURIFICATION
, vol.121, pp.112-117, 2016 (SCI-Expanded, Scopus)
2016
201615. Functional analysis of alcohol dehydrogenase (ADH) genes in Pichia pastoris
Karaoglan M., Karaoglan F. E., İNAN M.
BIOTECHNOLOGY LETTERS
, vol.38, no.3, pp.463-469, 2016 (SCI-Expanded, Scopus)
2014
201416. Screening of signal sequences for extracellular production of Aspergillus niger xylanase in Pichia pastoris
Karaoglan M., Yildiz H., İnan M.
Biochemical Engineering Journal
, vol.92, pp.16-21, 2014 (SCI-Expanded)
2011
201117. Effects of Baking and Boiling on the Nutritional and Antioxidant Properties of Sweet Potato [Ipomoea batatas (L.) Lam.] Cultivars
DİNÇER C., Karaoglan M., Erden F., Tetik N., TOPUZ A., ÖZDEMİR F.
PLANT FOODS FOR HUMAN NUTRITION
, vol.66, no.4, pp.341-347, 2011 (SCI-Expanded, Scopus)
Papers Presented at Peer-Reviewed Scientific Conferences
2019
20191. Development of Synthetic Pichia pastoris Alcohol Dehydrogenase (ADH) Promoters
Erden Karaoğlan F., Karaoğlan M., Yılmaz G., İnan M.
The 35th International Specialized Symposium on Yeasts, Antalya, Turkey, 21 - 25 October 2019, pp.45, (Summary Text)
2019
20192. Evaluation and Characterization of Heterologous Yeast Promoters in Pichia pastoris for Recombinant Protein Production
Erden Karaoğlan F., Karaoğlan M.
5th EUROPEAN CONFERENCE ON SCIENCE ART & CULTURE, Ankara, Turkey, 28 - 29 September 2019, pp.1, (Summary Text)
2019
20193. Recombinant Production of Chitin Deacetylase (CDA) in Pichia Pastoris
Karaoğlan M., Erden Karaoğlan F.
5th EUROPEAN CONFERENCE ON SCIENCE ART & CULTURE, Ankara, Turkey, 28 - 29 September 2019, pp.80, (Summary Text)
2019
20194. Expression of Full-Length and mature a-Amylase from Bacillus sp. in P. pastoris and Characterization of the Recombinant Enzyme
Karaoğlan M., Erden Karaoğlan F.
INTERNATIONAL CONFERENCE ON AGRONOMY AND FOOD SCIENCE & TECHNOLOGY, İstanbul, Turkey, 20 - 21 June 2019, pp.367, (Summary Text)
2019
20195. Heterologous Expression of Aspergillus niger Pectinase Gene in Pichia pastoris and its characterization
Karaoğlan M., Erden Karaoğlan F.
INTERNATIONAL CONFERENCE ON AGRONOMY AND FOOD SCIENCE & TECHNOLOGY, İstanbul, Turkey, 20 - 21 June 2019, vol.1, no.1, pp.262, (Summary Text)
2016
20166. Metabolic Engineering of Pichia pastoris for Lactic Acid Production
Ayas F., Karaoglan M., Inan M.
Pichia 2016, Antalya, Turkey, 3 - 06 April 2016, vol.1, no.1, pp.52, (Summary Text)
2016
20167. Characterization of ethanol metabolism genes in Pichia pastoris
KARAOGLAN M., ERDEN KARAOGLAN F., INAN M.
Pichia 2016, Antalya, Turkey, 3 - 06 April 2016, vol.1, no.1, pp.16, (Summary Text)
2016
20168. Cloning and Expression of Pullulanase from Bacillus subtilis BK07 and PY22 in Pichia pastoris
Erden Karaoğlan F., Karaoğlan M., Inan M., Karakaş B.
Pichia 2016, Antalya, Turkey, 3 - 06 April 2016, pp.55, (Summary Text)
2015
20159. Microbial Mannanase Production with Different Fermentation Methods And Characterization Of Enzyme-Produced
Yatmaz E., Turhan İ., Karaoglan M., Inan M., Karahalil E., Germeç M.
Northeast Agricultural & Biological Engineering Conference, Delaware, United States Of America, 12 - 15 July 2015, vol.1, no.1, pp.2, (Summary Text)
2015
201510. Large scale protein production process with Pichia pastoris ADH3 promoter
Karaoglan M., Erden Karaoglan F., Inan M.
8th Conference on Recombinant Protein Production RPP8, Palma, Spain, 22 - 24 April 2015, vol.1, no.1, pp.82, (Summary Text)
2014
201411. Utilization of Alcohol Dehydrogenase (ADH3) Promoter for Recombinant Protein Expression in Pichia pastoris
Karaoglan M., Erden F., Turhan I., Inan M.
European Biotechnology Congress 2014, Lecce, Italy, 15 - 18 May 2014, vol.1, no.1, pp.1, (Summary Text)
2014
201412. Identification and Characterization of Alcohol dehydrogenase genes in Pichia pastoris
INAN M., KARAOGLAN M., ERDEN F.
Pichia 2014, Protein Expression Conference, San Diego, California, United States Of America, 2 - 05 March 2014, vol.1, no.1, pp.42, (Summary Text)
2013
201313. Functional Characterization of ADH genes from Pichia pastoris
Karaoglan M., Erden F., Inan M.
VI. th International Bioengineering Congress "Human Welfare, Aydın, Turkey, 12 - 15 November 2013, vol.1, no.1, pp.75, (Summary Text)
2013
201314. Development of Alcohol Oxidase (AOX) Defective Strains of Pichia pastoris for Recombinant Protein Production
Karaoglan M., Inan M.
VI. th International Bioengineering Congress "Human Welfare, Aydın, Turkey, 12 - 15 November 2013, vol.1, no.1, pp.74, (Summary Text)
2013
201315. Development of Pichia pastoris host strain for recombinant protein production
INAN M., KARAOGLAN M., YILMAZ S.
VI. th International Bioengineering Congress "Human Welfare, Aydın, Turkey, 12 - 15 November 2013, vol.1, no.1, pp.42, (Summary Text)
2013
201316. Screening of Signal Sequences for Extracellular Production of A. niger Xylanase in Pichia pastoris
Yıldız H., Karaoglan M., Inan M.
VI. th International Bioengineering Congress "Human Welfare, Aydın, Turkey, 12 - 15 November 2013, vol.1, no.1, pp.73, (Summary Text)
2013
201317. Characterization of methanol expression regulatory protein (Mxr2) of Pichia pastoris
Inan M., Karaoglan M.
26th International Conference on Yeast Genetics and Molecular Biology, Frankfurt, Germany, 29 August - 03 September 2013, vol.1, no.2, pp.106, (Summary Text)
Books
2015
20151. Mikrobiyal Gelişim ve Beslenme
İNAN M., KARAOĞLAN M., ERDEN F., YILMAZ S.
in: Endüstriyel Mikrobiyolojiye Giriş, Turhan İ, Editor, Palme Yayın Dağıtım, Ankara, pp.21-45, 2015
2015
20152. Mikrobiyal Metabolizma
İNAN M., ERDEN F., YILMAZ S., KARAOĞLAN M.
in: Endüstriyel Mikrobiyolojiye Giriş, Turhan İ, Editor, Palme Yayın Dağıtım, Ankara, pp.46-74, 2015
2015
20153. Mikrobiyal Hücre Yapısı ve Fonksiyonu
İNAN M., YILMAZ S., KARAOĞLAN M., ERDEN F.
in: Endüstriyel Mikrobiyolojiye Giriş, Turhan İ, Editor, Palme Yayın Dağıtım, Ankara, pp.5-20, 2015
Funded Projects
2022 - Present
2022 - PresentPichia pastoris Mayasında Rekombinant Thaumatin Üretimi Kolon Kromatografisi ile Saflaştırılması ve Karakterizasyonu
Project Supported by Higher Education Institutions , BAP Research Project
KARAOĞLAN M. (Executive), ERDEN KARAOĞLAN F.
2022 - 2026
2022 - 2026D-Galakturonik Asitin Biyoteknoloji Alanında Katma Değeri Yüksek Ürün Üretiminde Kullanım İmkanlarının Araştırılması
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
Karaoğlan M. (Executive), Erden Karaoğlan F.
2023 - 2024
2023 - 2024Terapötik Peptit Tilapia Piscidin 4’ ün (TP4) Pichia pastoris Ekspresyon SistemindeRekombinant Üretimi ve HT-29 Kolorektal Kanser Hücreleri Üzerine Etkisinin Araştırılması
Emergency R&D Project of Group A
Kuzucu M., Karaoğlan M., Kılınç S.(Executive)
2019 - 2023
2019 - 2023Pichia pastoris aldehit dehidrogenaz (ALD) genlerinin karakterizasyonu ve asetat metabolizmasındaki rollerinin araştırılması
TUBITAK Project , 3501 - National Young Researcher Career Development Program
Karaoğlan M. (Executive), Erden Karaoğlan F.
2019 - 2023
2019 - 2023Pichia pastoriste rekombinant Liçenaz Üretimi ve Saflaştırılması
Project Supported by Higher Education Institutions , BAP Research Project
KARAOĞLAN M. (Executive), ERDEN KARAOĞLAN F.
2019 - 2023
2019 - 2023Lipaz enziminin Pichia pastoris Ekspresyon Sisteminde Rekombinant Üretimi Saflaştırılması ve Karakterizasyonu
Project Supported by Higher Education Institutions , BAP Research Project
ERDEN KARAOĞLAN F. (Executive), KARAOĞLAN M.
2017 - 2020
2017 - 2020Rhizomucor miehei L-Asparaginaz Enziminin P pastoris'te Rekombinant Üretimi
Project Supported by Higher Education Institutions , BAP Research Project
ERDEN KARAOĞLAN F. (Executive), KARAOĞLAN M.
2017 - 2019
2017 - 2019Heterolog Maya Promotorlarının Pichia pastoris ile Rekombinant Protein Üretiminde Değerlendirilmesi ve Karakterizasyonu
TUBITAK Project , 3001 - Initial R&D Projects Support Program
Erden Karaoğlan F. (Executive), Karaoğlan M.
2017 - 2019
2017 - 2019Pichia pastoris Mayasında Rekombinant Pektinaz Üretimi ve Enzimin Karakterizasyonu
Project Supported by Higher Education Institutions , BAP Research Project
KARAOĞLAN M. (Executive), ERDEN KARAOĞLAN F., ÇANKAYA M., KUZUCU M.
2017 - 2019
2017 - 2019Gıda Mühendisliği Bölümü Öğrenci Laboratuvarı Altyapı Projesi
Project Supported by Higher Education Institutions , BAP Research Project
ERTUGAY M. F. (Executive), ERDEN KARAOĞLAN F., AYGÜN T., KARAOĞLAN M., ŞAHİN Ö.
2012 - 2015
2012 - 2015Pichia Pastoris Alkol Dehidrogenaz Genlerinin Karakterizasyonu ve Rekombinant Protein Üretiminde Kullanılması
TUBITAK Project , 1001 - Program for Supporting Scientific and Technological Research Projects
İnan M.(Executive), Turhan İ.
2011 - 2012
2011 - 2012Pichia Pastoris Alkol Oksidaz (Aox1 Ve Aox2) Genlerinin İnaktif Edilmesi Ve Elde Edilen Suşun Rekombinant Protein Üretiminde Kullanılması
Project Supported by Higher Education Institutions , BAP MSc
Karaoğlan M., İnan M.(Executive)
Patent
2023
2023Determination of regulatory DNA regions of alcohol dehydrogenase 3 (ADH3) promoter and design of synthetic promoters for recombinant protein production
Patent
Registered / Approved, The Invention Registration Number: US11643663B2 , Standard Registration
Activities in Scientific Journals
2021 - Continues
2021 - ContinuesErzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Committee Member
Memberships and Roles in Scientific Organizations
2021 - Continues
2021 - ContinuesKOSGEB
Member of Science Committee
Peer Reviews in Scientific Publications
August 2022
August 2022BİOTECH STUDİES
National Scientific Refreed Journal
April 2022
April 2022MEDİTERRANEAN AGRİCULTURAL SCİENCES (AKDENİZ ÜNİVERSİTESİ ZİRAAT FAKÜLTESİ DERGİSİ)
National Scientific Refreed Journal
July 2020
July 2020HACETTEPE JOURNAL OF BİOLOGY AND CHEMİSTRY
National Scientific Refreed Journal
January 2018
January 2018American Journal of Biochemistry and Biotechnology
Other Indexed Journal
January 2017
January 2017American Journal of Biochemistry and Biotechnology
Other Indexed Journal
January 2016
January 2016American Journal of Biochemistry and Biotechnology
Other Indexed Journal
August 2015
August 2015Journal of Microbial & Biochemical Technology
Other Indexed Journal
Roles in Event Organizations
Nisan 2016
Nisan 2016Pichia 2016 Conference
Scientific Congress
İnan M., Karaoğlan M., Erden Karaoğlan F., Karakaş Budak B.
Antalya, Turkey
Congress and Symposium Activities
28 September 2019 - 29 September 2019
28 September 2019 - 29 September 20195 th European Conference on Science, Art Culture
Attendee
Ankara-Turkey
20 June 2019 - 21 June 2019
20 June 2019 - 21 June 2019INTERNATIONAL CONFERENCE ON AGRONOMY AND FOOD SCIENCE & TECHNOLOGY
Attendee
İstanbul-Turkey
01 April 2016 - 01 April 2016
01 April 2016 - 01 April 2016Pichia 2016
Attendee
Antalya-Turkey
01 May 2014 - 01 May 2014
01 May 2014 - 01 May 2014European Biotechnology Congress 2014
Attendee
-Italy
01 November 2013 - 01 November 2013
01 November 2013 - 01 November 2013VI. th International Bioengineering Congress "Human Welfare
Attendee
Aydın-Turkey
Scholarships
2012 - 2016
2012 - 2016BİDEB-2211-Yurtiçi Doktora Bursu
TUBITAK
Citations
Total Citations (WOS): 78
h-index (WOS): 5
Jury Memberships
January-2022
January 2022Doctoral Examination
- Akdeniz Üniversitesi
January-2022
January 2022Doctoral Examination
- Akdeniz Üniversitesi
July-2020
July 2020Doctoral Examination
- Akdeniz Üniversitesi
June-2020
June 2020Post Graduate
- Atatürk Üniversitesi
December-2017
December 2017