Education Information
2013 - 2019
2013 - 2019Doctorate
Erciyes University, Fen Bilimleri Enstitüsü, Turkey
2011 - 2013
2011 - 2013Postgraduate
Erciyes University, Fen Bilimleri Enstitüsü, Turkey
Dissertations
2019
2019Doctorate
Pirimidin ve imidazol çekirdeği içeren bileşiklerin sentezi ve in vitro sitotoksik aktivite çalışmaları
Erciyes University, Fen Bilimleri Enstitüsü
2013
2013Postgraduate
Rutenyum(II) aren komplekslerinin elektron konformasyonel-genetik algoritma (EC-GA) metodu ile farmakofor modellemesi ve 4D QSAR analizi
Erciyes University, Fen Bilimleri Enstitüsü
Research Areas
Chemistry
Organic Chemistry
Natural Sciences
Academic Titles / Tasks
2022 - Continues
2022 - ContinuesAssistant Professor
Erzincan Binali Yildirim University, İliç Dursun Yıldırım Meslek Yüksekokulu, Tıbbi Hizmetler ve Teknikler Bölümü
2019 - 2021
2019 - 2021Lecturer PhD
Yozgat Bozok University, Şefaatli Meslek Yüksekokulu, Veterinerlik
2010 - 2019
2010 - 2019Research Assistant
Erciyes University, Fen Bilimleri Enstitüsü
Published journal articles indexed by SCI, SSCI, and AHCI
2022
2022Synthesis, Characterization, Biological Activity and Molecular Modeling Studies of Novel Aminoguanidine Derivatives
Doğan N., ÇAĞLAR YAVUZ S., Sahin K., Orhan M. D., Muhammed H. K., Calis S., et al.
ChemistrySelect, vol.7, no.45, 2022 (SCI-Expanded)
2022
2022Antiproliferative activity and molecular docking studies of new 4-oxothiazolidin-5-ylidene acetate derivatives containing guanylhydrazone moiety
Al-Janabi I. A. S., Yavuz S., KÖPRÜ S., Tapera M., Kekeçmuhammed H., AKKOÇ S., et al.
Journal of Molecular Structure, vol.1258, 2022 (SCI-Expanded)
2021
2021Efficient synthesis and molecular docking studies of new pyrimidine-chromeno hybrid derivatives as potential antiproliferative agents
Yavuz S., AKKOÇ S., TÜZÜN B., Şahin O., SARIPINAR E.
Synthetic Communications, vol.51, no.14, pp.2135-2159, 2021 (SCI-Expanded)
2020
2020Single Crystal, DFT and Docking Studies of a Benzimidazolium Salt
AKKOÇ S., Yavuz S., TÜRKMENOĞLU B., İLHAN İ. Ö., AKKURT M.
Crystallography Reports, vol.65, no.7, pp.1173-1178, 2020 (SCI-Expanded)
2020
2020Synthesis of novel heterocyclic compounds containing pyrimidine nucleus using the Biginelli reaction: Antiproliferative activity and docking studies
Yavuz S., Akkoç S., Türkmenoğlu B., Sarıpınar E.
Journal of Heterocyclic Chemistry, vol.57, no.6, pp.2615-2627, 2020 (SCI-Expanded)
2020
2020The effect of stereoisomerism on the 4D-QSAR study of some dipeptidyl boron derivatives
Çatalkaya S., Sabancı N., Yavuz S., SARIPINAR E.
Computational Biology and Chemistry, vol.84, 2020 (SCI-Expanded)
2019
2019The cytotoxic activities of imidazole derivatives prepared from various guanylhydrazone and phenylglyoxal monohydrate
Yavuz S., AKKOÇ S., SARIPINAR E.
Synthetic Communications, vol.49, no.22, pp.3198-3209, 2019 (SCI-Expanded)
2018
2018Pharmacophore modelling and 4D-QSAR study of ruthenium(II) arene complexes as anticancer agents (inhibitors) by electron conformational-genetic algorithm method
Yavuz S., Sabancı N., SARIPINAR E.
Current Computer-Aided Drug Design, vol.14, no.1, pp.79-94, 2018 (SCI-Expanded)
2018
20184d-qsar study of some pyrazole pyridine carboxylic acid derivatives by electron conformational-genetic algorithm method
TÜZÜN B., Yavuz S., Sabancı N., SARIPINAR E.
Current Computer-Aided Drug Design, vol.14, no.4, pp.370-384, 2018 (SCI-Expanded)
2016
20164D-QSAR investigation and pharmacophore identification of pyrrolo[2,1-c][1,4]benzodiazepines using electron conformational–genetic algorithm method
Özalp A., YAVUZ S., Sabancı N., Çopur F., KÖKBUDAK Z., SARIPINAR E.
SAR and QSAR in Environmental Research, vol.27, no.4, pp.317-342, 2016 (SCI-Expanded)
Articles Published in Other Journals
2018
2018Density functional theory study of a silver N-heterocyclic carbene complex
Akkoç S., Çağlar Yavuz S., Akkurt M., Ersanlı C. C.
Journal of the Chinese Advanced Materials Society, vol.6, no.2, pp.112-122, 2018 (Peer-Reviewed Journal)
2017
20174D-QSAR analysis and pharmacophore modeling: propoxy methylphenyl oxasiazole derivatives by electron conformatitional-genetic algorithm method
TÜZÜN B., ÇAĞLAR YAVUZ S., SARIPINAR E.
Journal of Physical and Theoretical Chemistry, vol.14, no.2, pp.149-164, 2017 (Peer-Reviewed Journal)
2017
2017DFT studies and crystal structure of synthesized 1,3-bis(2-thiophenylmethyl)-4,5-dihydroimidazolidinium hexafluorophosphate salt
AKKOÇ S., TÜRKTEKİN ÇELİKESİR S., GÖK Y., ÇAĞLAR YAVUZ S., AKKURT M., ÖZDEMİR N.
Journal of the Turkish Chemical Society, Section A: Chemistry, vol.4, no.1, 2017 (Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2018
2018A Comprehensive 4D-QSAR Research on Phenylpyrazole Glutamic Acid Piperazine Scaffold by Electron Conformational-Genetic Algorithm Method
Özdoğan R., Çağlar Yavuz S., Sabancı N., Sarıpınar E.
4th Organic Chemistry Congress with International Participation, Antalya, Turkey, 4 - 07 October 2018
2018
2018Metil(2Z)-[(2Z)-2-{[(E)-amino{(2E)-[(4-metilfenil)metiliden]hidraziniliden}metil]imino}-3-fenil-4-okso-1,3-tiyoazolidin-5-iliden]asetat
ASLAN H. G., ÇAĞLAR YAVUZ S., SARIPINAR E.
II. ULUSLARARASIBİLİMSEL VE MESLEKİÇALIŞMALAR SEMPOZYUMU (BILMES 2018), 18 - 21 October 2018, pp.187-191
2018
2018REACTIONS OF AMINOGUANIDINE DERIVATIVES WITH DİMETHYL ACETYLENEDICARBOXYLATE
KÖKBUDAK Z., ÇAĞLAR YAVUZ S., KARATAŞ H., TÜRKMENOĞLU B., SARIPINAR E.
II.INTERNATIONAL SCIENTIFIC AND VOCATIONAL STUDIES CONGRESS, (BILMES SCI 2018), 5 - 08 July 2018
2018
2018Cytotoxic Activity Properties of Pyrimidine Derivative Compounds
ÇAĞLAR YAVUZ S., AKKOÇ S., SARIPINAR E.
II.INTERNATIONAL SCIENTIFIC AND VOCATIONAL STUDIES CONGRESS, (BILMES SCI 2018), 5 - 08 July 2018
2018
2018Synthesis and Characterization of Some Thiazolidine Derivatives
ÇAĞLAR YAVUZ S., Al JANABI I. A. S., SARIPINAR E., PATAT Ş.
INTERNATIONAL CONFERENCE ON PHYSICAL CHEMISTRY AND FUNCTIONAL MATERIALS (PCFM’18), ELAZIĞ, TÜRKIYE, 19 - 21 June 2018
2018
2018Synthesis of Some Imidazole Derivatives
ÇAĞLAR YAVUZ S., SARIPINAR E.
INTERNATIONAL CONFERENCE ON PHYSICAL CHEMISTRY AND FUNCTIONAL MATERIALS (PCFM’18), ELAZIĞ, TÜRKIYE, 19 - 21 June 2018
2018
2018Theorical and X-Ray Studies of An Ag-NHC Complex
ÇAĞLAR YAVUZ S., AKKOÇ S.
INTERNATIONAL CONFERENCE ON PHYSICAL CHEMISTRY AND FUNCTIONAL MATERIALS (PCFM’18), ELAZIĞ, TÜRKIYE, 19 - 21 June 2018
2018
2018THEORETICAL CALCULATIONS AND MOLECULAR DOCKING STUDY ANTICANCER EFFECT OF SYNTHESIZED SALT AGAINIST HELA CELL LINE
Akkoç S., Çağlar Yavuz S., Türkmenoğlu B.
INTERNATIONAL CONFERENCE ON PHYSICAL CHEMISTRY AND FUNCTIONAL MATERIALS (PCFM’18), ELAZIĞ, TÜRKIYE, 19 - 21 June 2018
2018
2018Synthesis and Characterization of Some Imidazole Derivatives
ÇAĞLAR YAVUZ S., SARIPINAR E.
International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2018), ANKARA, TÜRKIYE, 26 - 27 April 2018
2018
2018Synthesis of Pyrimidine Derivatives by Biginelli Reactions
ÇAĞLAR YAVUZ S., SARIPINAR E.
International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2018), ANKARA, TÜRKIYE, 26 - 27 April 2018
2017
2017Synthesized a New Organic Compound’s CytotoxicActivity Quantum Mechanics Calculations andDocking Studies
Akkoç S., Türkmenoğlu B., Çağlar Yavuz S.
2nd International Conference on Natural Products for Cancer Prevention and Therapy, 8 - 11 November 2017, vol.1, pp.1042
2017
2017"Synthesis Of 4,2 Copper Ion Incorporated Aminoguanidine Derivatives-Based Hybrid Nanoflowers
Çağlar Yavuz S., Somtürk Yılmaz B., Özdemir N., Sarıpınar E.
2nd NPCPT International Conference on Natural Products for Cancer Prevention and Therapy, Kayseri, Turkey, 8 - 11 November 2017, pp.1
2017
2017Synthesis of Hydrazino-Pyrimidine Derivatives by Multi-Component Reactions
ÇAĞLAR YAVUZ S., KARATAŞ H., SABANCI N., KÖKBUDAK Z., ÖZTÜRK KÜP F., SARIPINAR E.
5th International Bau Drug Design Congress, İstanbul, Turkey, 19 - 21 October 2017
2017
20174D-QSAR Analysis and Pharmacophore Modeling: Electron Conformational-Genetic Algorithm Approach for Imidazo Derivatives
ÇAĞLAR YAVUZ S., MEMİŞ Y., KÖPRÜ S., SARIPINAR E.
5th International Bau Drug Design Congress, 19 - 21 October 2017
2017
2017Reaction of N (aminoamidino) thiourea derivatives with dimethylacetylene dicarboxylate
Al JANABI I. A. S., ÇAĞLAR YAVUZ S., KÖPRÜ S., SARIPINAR E.
5th International Bau Drug Design Congress, 19 - 21 October 2017
2017
2017SYNTHESIS AND CHARACTERIZATION OF NEW HETEROCYCLICCOMPOUNDS
Çağlar Yavuz S., Sarıpınar E.
I. International Scientific and Vocational Studies Congress, Nevşehir, Turkey, 5 - 08 October 2017
2017
20174D-QSAR Investigation And Pharmacophore Identification Of Pyrrolo[2,1- C][1,4]Benzodiazepines Using Ec-Ga Method
Çağlar Yavuz S., Sarıpınar E.
BAU International Drug Design Symposium 2013: Novel Methods and Emerging Targets in Drug Discovery&Patented Drug Development, İstanbul, Turkey, 1 - 03 October 2017, pp.1
2017
2017Yeni Oksotiazolidin Türevlerinin Sentezi ve Karakterizasyonu
DOĞAN N., ÇAĞLAR YAVUZ S., KARATAŞ H., KÖPRÜ S., ŞAHİN O., KÖKBUDAK Z., et al.
Uluslararası Katılımlı 5. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, 30 March - 02 April 2017
2017
2017İmidazo[4,5] Piridin-2-on Türevlerinin Elektron Konformasyonal-Genetik Algoritma Metodu (EC-GA) İle 4D-Qsar Analizi
MEMİŞ Y., ÇAĞLAR YAVUZ S., KÖPRÜ S., SARIPINAR E.
Uluslararası Katılımlı 5. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, 30 March - 02 April 2017
2016
20164D QSAR Analysis of Some Dipeptidyl Boron Compounds Pharmacophore Identification andBioactivity Estimation
ÇATALKAYA S., ÇAĞLAR YAVUZ S., SABANCI N., SARIPINAR E.
2thINTERNATIONAL TURKIC WORLDCONFERANCE ON CHEMICAL SCIENCES ANDTECHNOLOGIES, Skopje, Macedonia, 26 - 30 October 2016
2016
2016SYNTHESIS OF GUANIDINE BASED OXOTHIAZOLIDINE DERIVATIVES AND QUANTUM CHEMİCAL CALCULATIONS
DOĞAN N., KARATAŞ H., ÇAĞLAR YAVUZ S., SARIPINAR E.
28. ULUSAL KİMYA KONGRESİ, Mersin, Turkey, 15 - 21 August 2016
2016
2016"Investigation of Effect of the Phenylpyrazole Glutamic Acid Piperazine Compounds as an Coagulation Inhibitor on P2Y12 (Ki) Receptor by 4D-QSAR EC-GA Method
Çağlar Yavuz S., Özdoğan R., Sarıpınar E.
4th International BAU Drug Design Congress, İstanbul, Turkey, 13 - 15 October 2016, pp.1
2015
2015Malonnitril, Aldehit ve Tiyosemikarbazon Bileşiklerinden Üç Bileşenli Yeni 4-Amino-5-karbonitril Pirimidin Sentezi ve HF Hesaplamaları
Çağlar Yavuz S., Karataş H., Geçen N., Öztürk Küp F., Sarıpınar E.
27. Ulusal Kimya Kongresi, Çanakkale, Turkey, 23 - 28 August 2015, pp.1
2015
2015Elektron Konformasyonel Genetik Algoritma 4D-QSAR Metodu İle Benzodiazepin Serisinde GI50 Aktivitesi için Farmakofor Belirlenmesi ve Biyoaktivite Hesabı
Özalp A., Çağlar Yavuz S., Kökbudak Z., Sarıpınar E.
3. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Antalya, Turkey, 20 March 2015 - 22 June 2022, pp.1
2015
2015Melanokortin-4 Türevlerinin Elektron Konformasyonel-Genetik Algoritma (EC-GA) Yötemi ile Nicel Yapı Aktivite İlişkisinin İncelenmesi ve Aktif Yapının Belirlenmesi
Özalp A., Çağlar Yavuz S., Kökbudak Z., Sarıpınar E.
3. İlaç Kimyası: İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Antalya, Turkey, 20 - 22 March 2015, pp.1
2012
2012Determination Of Pharmacophore Group And Bioactivity Account To Benzothienopyrimidinones, Compunds By Electron Conformational-Genetic Algorithm Method
Çağlar Yavuz S., Köprü S., Sarıpınar E.
10th Chemical Physics Congress (CPC-X), Ankara, Turkey, 10 - 12 October 2012, pp.1
2012
2012"Rutenyum(II) Aren Komplekslerinin Elektron Konformasyonel-Genetik Algoritma (EC-GA) Metodu İle Farmakofor Modellemesi ve 4D-QSAR Analizi
Çağlar Yavuz S., Köprü S., Sarıpınar E.
26.Ulusal Kimya Kongresi, Muğla, Turkey, 1 - 06 October 2012, pp.1
2012
20124D-QSAR EC-GA Metodu ile Benzotiyenopirimidin Bileşik Serisinin Farmakofor Grubunun Belirlenmesi ve Biyoaktivite Hesabı
Çağlar Yavuz S., Köprü S., Keskin H., Sarıpınar E.
III. Fiziksel Kimya Günleri Kongresi, Balıkesir, Turkey, 12 - 15 July 2012, pp.1
2011
20114D-Qsar EC-GA Metodu İle İmidazol Türevlerinin Farmakofor Grubunun Belirlenmesi ve Biyoaktivite Hesabı
Çağlar Yavuz S., Köprü S., Yanmaz E., Sarıpınar E.
25. Ulusal Kimya Kongresi, Erzurum, Turkey, 27 June - 02 July 2011, pp.1
2011
2011Piperazin Türevlerinin HIV-1 İnhibitörü Olarak Konformasyonel-Genetik Algoritma Yöntemi İle 4D-QSAR İncelenmes
Köprü S., Çağlar Yavuz S., Sarıpınar E., Yanmaz E.
25. Ulusal Kimya Kongresi, Erzurum, Turkey, 27 June - 02 July 2011, pp.1
Supported Projects
2019 - 2020
2019 - 2020Pirimidin Bazlı Bileşiklerin Sentezi
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Sarıpınar E.(Executive)
2018 - 2020
2018 - 2020Glikozillenmiş Kemoterapötik İlaçlar Geliştirme: Glikolize-Melphalan Türevlerinin Sentezi
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Sarıpınar E.(Executive), Çetin M., Doğan Ş. D.
2016 - 2019
2016 - 2019PİRİMİDİN VE İMİDAZOL ÇEKİRDEĞİ İÇEREN BİLEŞİKLERİN SENTEZİ VE İN VİTRO SİTOTOKSİK AKTİVİTE ÇALIŞMALARI
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Sarıpınar E.(Executive)
2017 - 2017
2017 - 2017GUANİDİN BAZLI OKSOTİAZOLİDİN TÜREVLERİNİN SENTEZİ VE KARAKTERİZASYONU
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Sarıpınar E.(Executive)
2014 - 2017
2014 - 2017Çok Bileşenli Reaksiyonlar: Ugi-Biginelli Melez Reaksiyonlarının Geliştirilmesi ve Heterosiklik Bileşiklerin Sentezi, Biyoaktivite ve 4D-QSAR Çalışmaları
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Kökbudak Z., Öztürk Küp F., Karataş H., Geçen N., Sarıpınar E.(Executive)
2012 - 2015
2012 - 2015EC-GA Metodu ile Diketopiperazin türevlerinde farmakofor grubun belirlenmesi ve bioaktivite tahmini : 4D-QSAR YAKLAŞIMI
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Sarıpınar E., İlhan İ. Ö.(Executive)
2011 - 2014
2011 - 2014Benzotiyenopirimidin Bileşik Serisinin Elektron Konformasyon Genetik Algoritma EC GA Yöntemi İle QSAR İncelenmesi
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Sarıpınar E.(Executive), Keskin H.
2012 - 2013
2012 - 2013Rutenyum II Aren Komplekslerinin Elektron Konformasyonel Genetik Algoritma EC GA Metodu ile Farmakofor Modellemesi ve 4D QSAR Analizi
Project Supported by Higher Education Institutions
Çağlar Yavuz S., Sarıpınar E.(Executive)
Patent
2022
2022