Doç. Dr. BETÜL ÇİÇEK

Yayın Ağı

Makaleler 28

1. Protective Effect of HMG-CoA Reductase Inhibitor Rosuvastatin on Doxorubicin-Induced Cognitive Impairment, Oxidative Stress and Neuroinflammation: Possible Role of CREB, ERK1/2, and BDNF

Yeni Y., ÇİÇEK B., HACIMÜFTÜOĞLU A., ÖZKARACA M., LAÇİN B. B.

Journal of Neuroimmune Pharmacology , cilt.20, sa.1, 2025 (SCI-Expanded, Scopus)

2. Investigating the therapeutic potential of transcranial direct current stimulation in an experimental Parkinson’s model through glutamate pathway

Danisman B., SİNEN O., Sinen A. G., ÇİÇEK B., DERİN N., Akçay G., et al.

Brain Structure and Function , cilt.230, sa.9, 2025 (SCI-Expanded, Scopus)

3. The role of antioxidant and anti-inflammatory mechanisms in the protective effects of vigabatrin against ovarian ischemia-reperfusion injury in a rat model

Hizal E., Uyar E., Bingul E., ÇİÇEK B., DEMİR Ö., MAMMADOV R., et al.

Journal of Ovarian Research , cilt.18, sa.1, 2025 (SCI-Expanded, Scopus)

4. Revealing the protective potential of D-(-)-Quinic acid against thioacetamide-induced hepatic encephalopathy in rats

Ciftel S., ÇİÇEK B., BOLAT İ., BULUT S., YILDIRIM S., SÜLEYMAN B., et al.

Scientific Reports , cilt.15, sa.1, 2025 (SCI-Expanded, Scopus)

5. Examination of PDK1/AKT/mTOR transcription and exosomal mRNA levels in human glioblastoma cell line treated with a combination of temozolomide and hesperidin

GENÇ S., ÇİÇEK B.

Naunyn-Schmiedeberg's Archives of Pharmacology , cilt.398, sa.11, ss.15731-15745, 2025 (SCI-Expanded, Scopus)

6. Panax Ginseng Protects Against Doxorubicin-Induced Testicular Injury in Male Rats by Modulating NF-κB/COX-2 and AR Pathways

Yeni Y., ÇİÇEK B., HACIMÜFTÜOĞLU A., ÖZKARACA M., Mokhtare B.

Molecular Neurobiology , cilt.62, sa.10, ss.12839-12850, 2025 (SCI-Expanded, Scopus)

7. Alpha-lipoic acid prevents doxorubicin-induced acute hepatorenal toxicity in rats by reducing oxidative and inflammatory stress to suppress autophagy

Yeni Y., ÇİÇEK B., HACIMÜFTÜOĞLU A., ÖZKARACA M., Mokhtare B.

Toxicology Research , cilt.14, sa.4, 2025 (SCI-Expanded, Scopus)

8. Trigonelline alkaloid is effective in preventing doxorubicin-induced lung damage

USLU H., ATİLA USLU G., ÇİÇEK B., BOLAT İ., YILDIRIM S.

Archives of Physiology and Biochemistry , cilt.131, sa.2, ss.169-176, 2025 (SCI-Expanded, Scopus)

9. Myricetin protects against doxorubicin-induced acute kidney injury in rats by mitigating oxidative damage and apoptotic response

Karadogan M. T., ÇİÇEK B., CİNİSLİ K. T., Mendil A. S., ÖZKARACA M., Yilmaz F., et al.

Frontiers in Pharmacology , cilt.16, 2025 (SCI-Expanded, Scopus)

10. Ameliorating effect of S-Allyl cysteine (Black Garlic) on 6-OHDA mediated neurotoxicity in SH-SY5Y cell line

Yeni Y., ÇİÇEK B., YILDIRIM S., BOLAT İ., HACIMÜFTÜOĞLU A.

Toxicology Reports , cilt.13, 2024 (Scopus)

11. Taxifolin as a novel therapeutic agent for epileptic seizures induced by caffeine-induced oxidative stress in rats.

YAŞAR H., ALTUNER D., Bulut S., ÇİÇEK B., GÜRSUL C., KUZUCU M., et al.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University , cilt.33, sa.8, ss.805-815, 2024 (SCI-Expanded, Scopus)

12. Morinda citrifolia protective effects on paclitaxel-induced testis parenchyma toxicity: An experimental study

GENÇ S., ÇİÇEK B., Yeni Y., KUZUCU M., HACIMÜFTÜOĞLU A., BOLAT İ., et al.

Reproductive Toxicology , cilt.127, 2024 (SCI-Expanded, Scopus)

13. AuNPs with Cynara scolymus leaf extracts rescue arsenic-induced neurobehavioral deficits and hippocampal tissue toxicity in Balb/c mice through D1R and D2R activation

ÇİÇEK B., HACIMÜFTÜOĞLU A., Yeni Y., KUZUCU M., GENÇ S., Cetin A., et al.

Environmental Toxicology and Pharmacology , cilt.107, 2024 (SCI-Expanded, Scopus)

14. Effects of benidipine, paracetamol, and their combination on postoperative and normal tissue pain thresholds.

Bedir Z., Ozkaloglu Erdem K. T., Doymus O., SÜLEYMAN H., YAVUZER B., ÇİÇEK B., et al.

Frontiers in pharmacology , cilt.14, ss.1326128, 2024 (SCI-Expanded, Scopus)

15. Virtual insights into the quercetin- Melampsora lini-derived effector AvrM14 interaction: An In silico exploration of plant defense mechanisms

Shadidizaji A., Tolga Cinisli K., WARDA M. A. A., ÇİÇEK B., Hacimuftoglu A.

Physiological and Molecular Plant Pathology , cilt.129, 2024 (SCI-Expanded, Scopus)

16. Syringic acid guards against indomethacin-induced gastric ulcer by alleviating inflammation, oxidative stress and apoptosis

FERAH OKKAY I., OKKAY U., ÇİÇEK B., KARATAŞ Ö., Yilmaz A., Yesilyurt F., et al.

Biotechnic and Histochemistry , cilt.99, sa.3, ss.147-156, 2024 (SCI-Expanded, Scopus)

17. Flavonoid-Rich Sambucus nigra Berry Extract Enhances Nrf2/HO-1 Signaling Pathway Activation and Exerts Antiulcerative Effects In Vivo

Çiçek B., Danışman B., Yıldırım S., Yüce N., Nikitovic D., Bolat İ., et al.

International Journal of Molecular Sciences , cilt.24, sa.20, 2023 (SCI-Expanded, Scopus)

18. Protective effect of melatonin and ascorbic acid combination on sepsis-induced lung injury: An Experimental study

ÜSTÜNDAĞ H., DEMİR Ö., ÇİÇEK B., HUYUT M. T., YÜCE N., Tavacı T.

Clinical and Experimental Pharmacology and Physiology , cilt.50, sa.8, ss.634-646, 2023 (SCI-Expanded, Scopus)

19. Chlorogenic Acid Attenuates Doxorubicin-Induced Oxidative Stress and Markers of Apoptosis in Cardiomyocytes via Nrf2/HO-1 and Dityrosine Signaling

ÇİÇEK B., HACIMÜFTÜOĞLU A., Yeni Y., DANIŞMAN B., ÖZKARACA M., Mokhtare B., et al.

Journal of Personalized Medicine , cilt.13, sa.4, 2023 (SCI-Expanded, Scopus)

20. Carnosic Acid Ameliorates Indomethacin-Induced Gastric Ulceration in Rats by Alleviating Oxidative Stress and Inflammation

DANIŞMAN B., ÇİÇEK B., YILDIRIM S., BOLAT İ., Kantar D., Golokhvast K. S., et al.

Biomedicines , cilt.11, sa.3, 2023 (SCI-Expanded, SSCI, Scopus)

21. Carvacrol prevents acrylamide-induced oxidative and inflammatory liver damage and dysfunction in rats

Cerrah S., ÖZÇİÇEK F., GÜNDOĞDU B., ÇİÇEK B., ÇOBAN T. A., SÜLEYMAN B., et al.

Frontiers in Pharmacology , cilt.14, 2023 (SCI-Expanded, Scopus)

22. Protective Effect of Adenosine Triphosphate against 5-Fluorouracil-Induced Oxidative Ovarian Damage in vivo

Ozer M., Ince S., ALTUNER D., SÜLEYMAN Z., ÇİÇEK B., GÜLABOĞLU M., et al.

Asian Pacific Journal of Cancer Prevention , cilt.24, sa.3, ss.1007-1013, 2023 (Scopus)

23. Effect of anakinra, tocilizumab, and the combination thereof on bladder ischemia-reperfusion damage in albino Wistar-type rats Efecto de la anakinra, el tocilizumab y la combinación de ambos sobre el daño por isquemia-reperfusión vesical en ratas albinas tipo Wistar

BİÇER Ş., SÜLEYMAN B., MAMMADOV R., Yavuzer B., ÇİÇEK B., ALTUNER D., et al.

Investigacion Clinica (Venezuela) , cilt.64, sa.3, ss.368-378, 2023 (SCI-Expanded, Scopus)

24. Artichoke (Cynara Scolymus) Methanolic Leaf Extract Alleviates Diethylnitrosamine-Induced Toxicity in BALB/c Mouse Brain: Involvement of Oxidative Stress and Apoptotically Related Klotho/PPARγ Signaling

ÇİÇEK B., GENÇ S., Yeni Y., KUZUCU M., Cetin A., YILDIRIM S., et al.

Journal of Personalized Medicine , cilt.12, sa.12, 2022 (SCI-Expanded, Scopus)

25. Neuroprotective effect of bromelain in 6-hydroxydopamine induced in vitro model of Parkinson's disease

FERAH OKKAY I., OKKAY U., ÇİÇEK B., Yilmaz A., Yesilyurt F., Mendil A. S., et al.

MOLECULAR BIOLOGY REPORTS , cilt.48, sa.12, ss.7711-7717, 2021 (SCI-Expanded, Scopus)

26. Achillea millefolium alleviates testicular damage in paclitaxel-intoxicated rats via attenuation of testicular oxido-inflammatory stress and apoptotic responses.

OKKAY U., FERAH OKKAY I., ÇİÇEK B., AYDIN İ. Ç., Ertugrul M. S., Bayram C., et al.

Andrologia , cilt.53, 2021 (SCI-Expanded, Scopus)

27. Beneficial Effects of Achillea Millefolium and Aesculum Hippocastanum Extracts on Glutamate Excitotoxicity in the Primary Cultured Neurons.

FERAH I., OKKAY U., ÇİÇEK B., Yeşilyurt F., YILMAZ A., HACIMÜFTÜOĞLU A.

Advances in Clinical Toxicology , cilt.4, sa.4, 2019 (Hakemli Dergi)

28. Glutamat Eksitotoksisitesi Oluşturulan Primer Kortikal Nöron Kültürlerinde Parietinin Nöroprotektif Etkisinin İncelenmesi

GÜNDOĞDU G., Taghizadehghalehjoughi A., ÇİÇEK B., Senol O., Nalci K. a., DEMİRKAYA A. K., et al.

Atatürk Üniversitesi Veteriner Bilimleri Dergisi , cilt.13, sa.2, ss.165-173, 2018 (Scopus, TRDizin)

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler 25

1. Apocynin Counteracts 6-OHDA Induced Neurotoxicity in SHSY5Y Cells and Modulates Oxidoinflammatory Responses

ÇİÇEK B., HAYME S.

3rd International Congress of Health Sciences and Biotechnology-Bilecik, 3 - 07 Ekim 2022, (Tam Metin Bildiri)

2. Therapeutic potential of bromelain in 6-hydroxydopamine rat model of parkinson's disease

Çiçek B., Gül M., Taghizadehghale A., Okkay U., Yıldırım S., Ferah Okkay I., et al.

33rd ECNP, 12 - 15 Eylül 2020, ss.438-439, (Özet Bildiri)

3. Investigation of Wound Healing and Antimicrobial Effects of ZnO Nanoparticles Synthesized Using Mentha longifolia L. Essential Oil

SEZEN S., NALCI K. A., DEMİR A. Y., BAYRAM C., ÇİÇEK B., OKKAY U., et al.

Uluslararası Biyoteknoloji Kongresi, 5 - 07 Mart 2020, (Özet Bildiri)

4. Determination of Glutathione Reductase Enzyme Activity in Melatonin Administered Rats’s Heart Tissue

ÇİÇEK B., ŞENTÜRK E., GÜL M., ÇELEBİ F., ÜSTÜNDAĞ H., ŞENTÜRK M.

45. Ulusal Fizyoloji Kongresi, Aydın, Türkiye, 31 Ekim - 03 Kasım 2019, cilt.227, (Özet Bildiri)

5. Bromelain Makes Glioblastoma Multiforme Cells Susceptible to the Temozolomide Cytotoxicity by Affecting the Activities of Carbonic Anhydrase and Some Antioxidant Enzymes

ÇİÇEK B., GÜL M., Taghizadehghalehjoughi A., OKKAY U., durmuş u., yeşilyurt f., et al.

45. Ulusal Fizyoloji Kongresi, Aydın, Türkiye, 31 Ekim - 03 Kasım 2019, cilt.227, (Özet Bildiri)

6. Determination of Acetylcholinesterase Enzyme Activity in Liver Tissues of Rats with Hyperthyroidism

ÇİÇEK B., ÇELEBİ F., GÜL M., ŞENTÜRK M., ÜSTÜNDAĞ H., ŞENTÜRK E.

45. Ulusal Fizyoloji Kongresi, Aydın, Türkiye, 31 Ekim - 03 Kasım 2019, cilt.227, (Özet Bildiri)

7. PYCNOGENOL HIGH DOSE DECREASED GLUTAMATE INDUCED TOXICITY: IN VITRO STUDY

ÇİÇEK B., TAGHİZADEHGHALE A., HACIMÜFTÜOĞLU A.

FENS 2019 regional meeting, Belgrade, Sırbistan, 10 - 13 Temmuz 2019, (Özet Bildiri)

8. Gliserol Guaiacol maddesinin nöron koruyucu ve antikanser etkilerinin araştırılması: in vitro deney

ÇİÇEK B., TAGHİZADEHGHALE A., ŞENTÜRK E., ŞENTÜRK M., GÜL M., HACIMÜFTÜOĞLU A.

17. ULUSAL SİNİRBİLİM KONGRESİ, Türkiye, 4 - 07 Nisan 2019, (Özet Bildiri)

9. Pirogallol maddesinin nöron koruyucu ve antikanser etkilerinin araştırılması: in vitro çalışma

ÇİÇEK B., TAGHİZADEHGHALE A., ŞENTÜRK E., ŞENTÜRK M., HACIMÜFTÜOĞLU A., GÜL M.

17. ULUSAL SİNİRBİLİM KONGRESİ, Türkiye, 4 - 07 Nisan 2019, (Özet Bildiri)

10. Akut Kobalt Toksikasyonunun Karaciğer, Böbrek Ve Kalp Dokularında Oluşturduğu Oksidatif Stres Üzerine Likopenin Koruyucu Etkileri,

BARDAŞ ÖZKAN E., ÇİÇEK B., ARSLAN Y. K.

3. Uluslararası sağlık bilimleri kongresi, 29 kasım-1 aralık, Ankara, 2018., Ankara, Türkiye, 29 Kasım - 01 Aralık 2018, (Özet Bildiri)

11. Is Oxytocin Proper for Cancer Adjuvant Therapy?

Taghizadehghalehjoughi A., ÇİÇEK B., HACIMÜFTÜOĞLU A., GÜL M.

2nd International Cell Death Research Congress, 1 - 04 Kasım 2018, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

12. E Vitamini ve Selenyumun Yüksek Dozda Prednizolon Uygulanan Sıçanların Eritrositlerindeki Oksidan - Antioksidan Denge Üzerine Koruyucu Etkisi

ÇİÇEK B., BARDAŞ E., ARSLAN Y. K.

3. Uluslararası Sağlık bilimleri kongresi, 29 Kasım - 01 Aralık 2018, (Tam Metin Bildiri)

16. ANTICANCER AND ANTI-APOPTOTIC MECHANISMS OF ZN2 LOADED FE3O4-SIO2-NH2- (ZINPYR-1) NANOCOMPOSITE IN SH-SY5Y NEUROBLASTOMA CELLS

GÜNDOĞDU G., DODURGA Y., DEMİRKAYA MİLOĞLU F., SEÇME M., ÇİÇEK B., polatdemir e., et al.

2ND BRAIN RESEARCH SCHOOL, 6 - 12 Kasım 2017, (Özet Bildiri)

17. PROTECTIVE EFFECT OF INDOMETHACIN, LACIDIPINE ANDOXCARBAZEPINE ON GLUTAMATE TOXICITY IN RAT OLFACTORYBULB: AN IN VITRO STUDY

Taghizadehghalehjoughi A., ÇİÇEK B., GÜNDOĞDU G., Hacimuftuoglu A.

2ND BRAIN RESEARCH SCHOOL, 6 - 12 Kasım 2017, (Özet Bildiri)

22. PROTECTIVE EFFECT OF ZN2 LOADED FE3O4-SIO2-NH2- (ZINPYR-1) NANOCOMPOSITE ON GLUTAMATE EXERCISE TOXICITY IN PRIMARY CORTICAL NEURON CELL CULTURE’

GÜNDOĞDU G., DEMİRKAYA MİLOĞLU F., Nalci K. a., ÇİÇEK B., Taghizadehghalehjoughi A., polatdemir e., et al.

ACTA PHYSIOLOGICA (43. fizyoloji kongresi), 7 - 10 Eylül 2017, (Özet Bildiri)

23. THE CYTOTOXIC AND GENOTOXIC EFFECTS OF DAIDZEIN IN HT-29 HUMAN COLON ADENOCARCINOMA CELLS

GÜNDOĞDU G., DODURGA Y., ÇETİN M., SEÇME M., ÇİÇEK B.

ACTA PHYSIOLOGICA (43. Fizyoloji Kongresi), 7 - 10 Eylül 2017, (Özet Bildiri)

24. INVESTIGATION OF EFFECTS OF RHEUM RIBES EXTRACT ON HUMAN DERMAL FIBROBLAST CELL LINE

GÜNDOĞDU G., gundogdu k., Nalci K. a., ÇİÇEK B., Senol O., YILMAZ TAŞCI Ş., et al.

ACTA PHYSIOLOGICA (43. Fizyoloji Kongresi), 7 - 10 Eylül 2017, (Özet Bildiri)

25. DETERMINATION OF SERUM VISFATIN AND APELIN LEVELS IN ACUTE CORANARY SYNDROME PATIENTS AND DETECTION OF ASSOCIATION WITH CORONARY ARTERY DISEASE

GÜNDOĞDU G., KOZA Y., ÇİÇEK B., DEMİRKAYA MİLOĞLU F., GÜNDOĞDU F.

ACTA PHYSIOLOGICA (43.Fizyoloji Kongresi), 7 - 10 Eylül 2017, (Özet Bildiri)

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