Copy For Citation
Kwon S. J., Lee K. B., Solakyıldırım K., Masuko S., Ly M., Zhang F., ...More
Angewandte Chemie - International Edition, vol.51, no.47, pp.11800-11804, 2012 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
51
Issue:
47
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Publication Date:
2012
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Doi Number:
10.1002/anie.201205112
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Journal Name:
Angewandte Chemie - International Edition
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Page Numbers:
pp.11800-11804
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Keywords:
carbohydrates, DNA, glycoconjugates, signal amplification, ultrasensitive detection
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Erzincan Binali Yildirim University Affiliated:
No
Abstract
Tiny amounts of carbohydrates (ca. 1zmol) can be detected quantitatively by a real-time method based on the conjugation of carbohydrates with DNA markers (see picture). The proposed method (glyco-qPCR) provides uniform, ultrasensitive detection of carbohydrates, which can be applied to glycobiology, as well as carbohydrate-based drug discovery. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.