Atıf İçin Kopyala
Kwon S. J., Lee K. B., Solakyıldırım K., Masuko S., Ly M., Zhang F., ...Daha Fazla
Angewandte Chemie - International Edition, cilt.51, sa.47, ss.11800-11804, 2012 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
51
Sayı:
47
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Basım Tarihi:
2012
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Doi Numarası:
10.1002/anie.201205112
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Dergi Adı:
Angewandte Chemie - International Edition
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.11800-11804
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Anahtar Kelimeler:
carbohydrates, DNA, glycoconjugates, signal amplification, ultrasensitive detection
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Erzincan Binali Yıldırım Üniversitesi Adresli:
Hayır
Özet
Tiny amounts of carbohydrates (ca. 1zmol) can be detected quantitatively by a real-time method based on the conjugation of carbohydrates with DNA markers (see picture). The proposed method (glyco-qPCR) provides uniform, ultrasensitive detection of carbohydrates, which can be applied to glycobiology, as well as carbohydrate-based drug discovery. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.