Changes in antimicrobial resistance and outcomes of health care-associated infections

Aydin, Mehtap; AZAK KARALİ, EMEL; Bilgin, Huseyin; Menekse, Sirin; Asan, Ali; Mert, Habibe; YULUĞKURAL, ZERRİN; Altunal, Lutfiye; Hatipoglu, Cigdem; Ertem, Gunay; Altunok, Elif; Demirkaya, Melike; Ceviker, Sevil; Akgul, Fethiye; Memis, Zeynep; Konya, Petek; Azap, Alpay; Aydin, Gule; Korkmaz, Derya; Karakoc, Zehra; YAPAR, DERYA; KARAKEÇİLİ, FARUK; Gunal, Ozgur; Keske, Siran; Kapmaz, Mahir; KADER, ÇİĞDEM; Demirel, Aslihan; Ergonul, Onder

doi:10.1007/s10096-020-04140-y

Changes in antimicrobial resistance and outcomes of health care-associated infections

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Aydin M., AZAK KARALİ E., Bilgin H., Menekse S., Asan A., Mert H. T. E., ...More

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, vol.40, pp.1737-1742, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 40
Publication Date: 2021
Doi Number: 10.1007/s10096-020-04140-y
Journal Name: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, CAB Abstracts, EMBASE, Environment Index, MEDLINE, Public Affairs Index, Veterinary Science Database
Page Numbers: pp.1737-1742
Erzincan Binali Yildirim University Affiliated: Yes

Abstract

To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.