The role of oleuropein against nanocomposite toxicity in fruit fly: evidence for lifespan extension

Atici T., Altun Çolak D.

CARYOLOGIA, cilt.73, sa.3, ss.127-132, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 73 Sayı: 3
  • Basım Tarihi: 2020
  • Doi Numarası: 10.13128/caryologia-226
  • Dergi Adı: CARYOLOGIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.127-132
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

The effect of zinc oxide/titanium dioxide nanocomposite the lifespan of the fruit fly Drosophila melanogaster and the protective role of oleuropein, a strong antioxidant, against the zinc oxide/titanium dioxide were investigated. Chemicals prepared in different concentrations (0.005, 0.1, 0.5, and 1 g/L for zinc oxide/titanium dioxide; 0.1 mmol/L for oleuropein) have been separately applied to female and male populations of D. melanogaster for the control and application groups. In both female and male populations, it has been observed that zinc oxide/titanium dioxide has decreased the lifespan and oleuropein has increased the lifespan according to the control group, depending on the concentration. These findings demonstrate the beneficial effect of oleuropein, suggested as a protective role in the prevention of zinc oxide/titanium dioxide induced developmental toxicity.