Aortic propagation velocity in the prediction of coronary artery disease severity

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BAKIRCI E. M., DEĞİRMENCİ H., DUMAN H., Demirelli S., HAMUR H., BÜYÜKLÜ M., ...Daha Fazla

Biomedical Papers, cilt.166, sa.1, ss.51-56, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 166 Sayı: 1
  • Basım Tarihi: 2022
  • Doi Numarası: 10.5507/bp.2021.001
  • Dergi Adı: Biomedical Papers
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.51-56
  • Anahtar Kelimeler: APV, CIMT, CAD, SYNTAX score
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

© 2022 The Authors.Aims. To investigate the association of the aortic propagation velocity (APV) with coronary artery disease (CAD) in patients with stable angina pectoris (SAP) through SYNTAX scores (SS). Methods. The study population comprised 214 SAP subjects who received a coronary angiography. The APV and carotid intima–media thickness (CIMT) were examined and SS was calculated. Subjects were grouped following specific SS criteria: SS less than 22 (low) and SS greater than or equal to 22 (high). Results. High SS subjects had lower APV compared to low SS [39.0 (32.0-51.7) vs. 55.0 (45.0-62.0) cm/s, respectively; P<0.001] and higher CIMT (0.86 ± 0.24 vs. 0.74 ± 0.21 mm, respectively; P<0.001). APV demonstrated a negative correlation with the CIMT (r=-0.239, P<0.001), age (r=-0.188, P=0.006), and SS (r=-0.561, P<0.001) and showed a positive association with LV ejection fraction (r=0.163, P=0.017). APV, CIMT, diabetes, low-density lipoprotein cholesterol (LDL-C), and age were determined to be markers independently of a high SS. Conclusion. APV, CIMT, diabetes, LDL-C and age are independently linked to the CAD severity of SAP subjects. Decreased APV, an indicator of subclinical atherosclerosis, may independently help determine the severity of atherosclerotic CAD in SAP patients.