Akademik Veri Yönetim Sistemi
3rd Eurasia Biochemical Approaches & Technologies (EBAT), Antalya, Türkiye, 4 - 07 Kasım 2021, ss.109
The genus Verbascum L. (Scrophulariaceae) known as “Sığır kuyruğu” in Anatolia is represented by 245 species, 194 of them are endemic. Verbascum genus is one of the plant species used in the treatment of various diseases in traditional medicine as an expectorant, diuretic, demulcent, sedative, antibacterial, antiviral, antifungal, antiulcerogenic, antioxidant, cytotoxic, antitumor, antihepatoma, immunomodulatory, and antiulcerogenic effects.1,2 It was also used for healing wounds in animal care. Previous studies on Verbascum species have reported the presence of iridoids, phenylethanoids, lignans, saponins, flavonoids, and sterols.3 Verbascum leiocarpum is an endemic species in Turkey growing in Erzincan. To the best of our knowledge, there is no study about the phytochemical content of V. leiocarpum has been published. In this study, the isolation and characterization of secondary metabolites of Verbascum leiocarpum were aimed. The plant materials were collected from Kemaliye- Erzincan, in June 2019. The aerial parts were extracted with methanol:water (7:3) under room conditions for 24 hours. The crude extract was fractionated using flash chromatography over a prepacked C18 column. The separation process has achieved the isolation of two iridoid glucosides named catalpol (500 mg) and ajugol (750 mg). The occurrence of catalpol and ajugol in Verbascum species was previously reported.4,5 Also, this study reports the iridoid glycoside contents of V. leiocarpum plant for the first time.