The value of Proton MR-spectroscopy in the differentiation of brain tumours from non-neoplastic brain lesions

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Aydin H., Sipahioǧlu S., Aydin Oktay N., Altin E., Kizilgöz V., Hekimoglu B.

JBR-BTR, cilt.94, sa.1, ss.1-10, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 94 Sayı: 1
  • Basım Tarihi: 2010
  • Doi Numarası: 10.5334/jbr-btr.470
  • Dergi Adı: JBR-BTR
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1-10
  • Anahtar Kelimeler: Brain, Brain neoplasms, Diseases, Magnetic resonance (MR), MR, Spectroscopy
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Hayır

Özet

Purpose: Our aim was to evaluate the efficacy of Proton-MR Spectroscopy for the differentiation of cranial masses from non-neoplastic brain disorders. Material and method: 33 patients with intracranial mass lesions, 29 patients with non-neoplastic brain lesions: Ischemic-demyelinating-metabolic-benign cystic mass group; As a whole 62 patients: 30 males and 32 females were included in this study. Results: In brain tumours, average Cho/NAA ratio 2.84-NAA/Cr ratio was 0.97, Cho/Cr ratio 2.42 and Cho/MI ratio was 3.51. In non-neoplastic group; NAA/Cr ratio was extremely higher than tumour group, the other ratios were far lower than cranial mass lesions. Average Cho/NAA ratio: 0.50 ± 0.15, Cho/Cr ratio: 1.05 ± 0.14, Cho/MI ratio: 1.07 ± 0.73. Conclusion: Higher Cho/NAA and Cho/MI ratios with lower NAA/Cr ratio were most likely to be malignant. Additional lipid and lactate peaks were generally seen in malignant group.