Akademik Veri Yönetim Sistemi
MINIMALLY INVASIVE NEUROSURGERY, cilt.49, sa.6, ss.359-361, 2006 (SCI-Expanded)
Background: Baroreceptor reflexes are regulated by nerve terminals of the glossopharyngeal and vagal nerves. The body of pressure-sensitive neurons of these nerves is located in the petrosal ganglion of both nerves. We examined whether there is a relationship between the neuron numbers of the inferior ganglion of the glossopharyngeal nerve and blood pressure values. Methods: Petrosal ganglions were examined in 18 male hybrid rabbits divided into three equal groups: Group A normotensive (TA = 90-100 mmHg), Group B hypertensive (TA > 100 mmHg); and Group C hypotensive (TA < 90 mmHg). After examination of blood pressure for one week, all animals were sacrificed, and the petrosal ganglions extracted bilaterally and examined histopathologically using the physical dissector method. Results: The mean (+/- SD) neuronal density was: Group A 8700 200, Group B 7800 250 and Group C 9800 300, respectively. The difference between the groups B and C as compared to A was significant (p < 0.01) while the difference between Groups B and C was highly significant (p < 0.001). Conclusions: An inverse relationship was noticed between the neuronal density in the petrosal ganglion and blood pressure values with potential implications in the study of the etiology of hypertension.