Copy For Citation
Huyut Z., BAKAN N., YILDIRIM S., Alp H. H.
MEDICAL SCIENCE MONITOR BASIC RESEARCH, vol.24, pp.47-58, 2018 (ESCI)
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Publication Type:
Article / Article
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Volume:
24
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Publication Date:
2018
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Doi Number:
10.12659/msmbr.908504
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Journal Name:
MEDICAL SCIENCE MONITOR BASIC RESEARCH
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Journal Indexes:
Emerging Sources Citation Index (ESCI), Scopus
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Page Numbers:
pp.47-58
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Keywords:
Bone Density, Dexamethasone, Osteoporosis, Phosphodiesterase 5 Inhibitors, NITRIC-OXIDE, MINERAL DENSITY, ANTIOXIDANT ACTIVITY, COENZYME Q(10), DNA-DAMAGE, STRESS, OVARIECTOMY, EXPRESSION, SUSCEPTIBILITY, METABOLISM
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Erzincan Binali Yildirim University Affiliated:
No
Abstract
Background: The aim of this study was to evaluate the effects of the phosphodiesterase-5 (PDE-5) inhibitors, zaprinast and avanafil, on NO signalling pathway, bone mineral density (BMD), epiphyseal bone width, bone marrow angiogenesis, and parameters of oxidative stress in a rat model of glucocorticoid-induced osteoporosis (GIOP).