Research Information System
9th Joint Meeting of AFERP, ASP, GA, JSP, PSE and SIF, Copenhagen, Denmark, 24 - 27 July 2016, vol.82, (Summary Text)
Cotinus coggygria Scop. (syn.: Rhus cotinus L.) (Anacardiaceae) is a deciduous and slow growing shrub, widespread mainly in South and Central Europe, South Russia, Crimea, Caucasia, Latakia and Turkey [1]. Turkish local names of the plant are “tetre, boyacı sumağı, sarıboya ağacı, sarıcan, sarı yaprak, pamuklu sumak and duman ağacı”. The infusion prepared from the leaves of the plant is used in Turkish folk medicine as antidiabetic, antiseptic, anti-inflammatory, antimicrobial, antihaemorrhagic and wound healing agent [2,3]. According to phytochemical studies, polyphenols, flavonoids and tannins have been isolated from different parts of C. coggygria. The biological activity studies of this species indicated antidiabetic, antioxidant, cytotoxic, antigenotoxic, antimicrobial, antiviral, hepatoprotective, antiinflammatory activities [4].
In the present study, dried and powdered leaves of C. coggygria were extracted with methanol. The extract was dissolved in water and partitioned with petroleum ether, chloroform, ethyl acetate and n-butanol, respectively. Separation of the ethyl acetate by chromatographic means (sephadex, silica gel and vacuum liquid chromatography) gave five phenolic compounds: 1,2,3,4,6-penta-O-galloyl-β-D-glucose, gallocatechin, methyl gallate, myricetin-3-O-rhamnoside and myricetin-3-O-galactoside. The structures of these compounds were determined by extensive spectroscopic analyses.