Proliferation of trophoblasts and Ki67 expression in preeclampsia


Kaya B., Nayki U., NAYKI C., ULUĞ P., Oner G., Gultekin E., ...More

ARCHIVES OF GYNECOLOGY AND OBSTETRICS, vol.291, no.5, pp.1041-1046, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 291 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1007/s00404-014-3538-4
  • Journal Name: ARCHIVES OF GYNECOLOGY AND OBSTETRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1041-1046
  • Erzincan Binali Yildirim University Affiliated: Yes

Abstract

Preeclampsia is a pregnancy-specific disease with the increased risk of maternal morbidity and mortality. It is characterised by placental vascular dysfunction. Despite the numerous studies on preeclampsia, studies evaluating proliferation of villous trophoblasts in preeclamptic placentas are limited. Ki67 is a proliferation marker that expresses in the nuclei of proliferating cells. In this study, we examined the proliferation of villous trophoblasts in placentas of preeclamptic patients by using Ki67 and compared it with placentas of normal pregnant patients.