Detection of insulin-like growth factor receptor-1 in the human cremaster muscle and its role in the etiology of the undescended testis

ÖZDAMAR, MUSTAFA; Sahin, Sevinc; Zengin, Kursad; SEÇKİN, Selda; GURDAL, Mesut

doi:10.1016/j.asjsur.2018.02.005

Detection of insulin-like growth factor receptor-1 in the human cremaster muscle and its role in the etiology of the undescended testis

ÖZDAMAR M. Y., Sahin S., Zengin K., SEÇKİN S., GURDAL M.

ASIAN JOURNAL OF SURGERY, cilt.42, sa.1, ss.290-296, 2019 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 42 Sayı: 1
Basım Tarihi: 2019
Doi Numarası: 10.1016/j.asjsur.2018.02.005
Dergi Adı: ASIAN JOURNAL OF SURGERY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.290-296
Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

Purpose: Previous studies of undescended testis (UT) has focused on insulin-like hormone 3 (INSL3), the genitofemoral nerve, and androgens in the testicular descent. Leydig cells, which are under the control of insulin-like growth factor-1 (IGF1), produce both androgens and INSL3. We aimed to investigate whether insulin-like growth factor receptor-1(IGFR1) exists in the cremaster muscle (CM) complex and is associated with normally descended testis as well as UT cases in humans.