10. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi, Ankara, Türkiye, 27 - 28 Ağustos 2022, cilt.1, sa.1, ss.224-228
Introduction: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of motor
neurons, the etiology of which is not yet clear. In the presented case, early brain diffusion MR imaging
findings of the patient who was diagnosed with definite ALS were discussed. Case: A 65-year-old male
patient, whose symptoms started 6 months ago, met the definite ALS diagnostic criteria. Central nervous
system routine MRI findings were within normal limits. On diffusion MRI, there was a hyperintense
appearance suggesting a neurodegenerative process in the motor cortex and corticospinal tractus.
Discussion: While the findings are normal in routine brain MRI sequences in ALS patients, hyperintense
appearance in the precentral gyrus and corticospinal tract only in diffusion MRI has been rarely
reported in the literature. In this case, hyperintensity in the precentral gyrus and corticospinal tract was
observed in diffusion MRI, and it was thought that this situation might be related to the rapid
neurodegenerative process.