Activation of Two Different Drugs Used in Alzheimer's Disease Treatment on Human Carbonic Anhydrase Isozymes I and II Activity: an In Vitro Study


DİLEK E.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, no.2, ss.164-168, 2017 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 14 Konu: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.4274/tjps.43434
  • Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
  • Sayfa Sayısı: ss.164-168

Özet

Objectives: Human carbonic anhydrase I and II (hCAI, II) isoenzymes were purified from human erythrocyte. Kinetic interactions between the enzymes and memantine and donepezil, two different drugs used in Alzheimer's disease (AD) treatment, were investigated.