Activation of Two Different Drugs Used in Alzheimer's Disease Treatment on Human Carbonic Anhydrase Isozymes I and II Activity: an In Vitro Study

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DİLEK E.

TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.14, sa.2, ss.164-168, 2017 (ESCI)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 14 Sayı: 2
• Basım Tarihi: 2017
• Doi Numarası: 10.4274/tjps.43434
• Dergi Adı: TURKISH JOURNAL OF PHARMACEUTICAL SCIENCES
• Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
• Sayfa Sayıları: ss.164-168
• Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
• Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

Objectives: Human carbonic anhydrase I and II (hCAI, II) isoenzymes were purified from human erythrocyte. Kinetic interactions between the enzymes and memantine and donepezil, two different drugs used in Alzheimer's disease (AD) treatment, were investigated.