Effect of Rutin on Gentamicin-Induced Ototoxicity in Rats: A Biochemical and Histopathological Examination

Salcan İ., Dilber M., Bayram R., Suleyman E., Yazıcı G. N., Coban A., ...Daha Fazla

ENT UPDATES, cilt.11, sa.1, ss.8-13, 2021 (Hakemli Dergi) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5152/entupdates.2021.887158
  • Dergi Adı: ENT UPDATES
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.8-13
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

Objective: Gentamicin is a broad-spectrum aminoglycoside antibiotic administered parenterally for moderate to severe gram-negative infections. Ototoxicity is an important side effect that limits gentamicin use. The aim of this study is to investigate the effect of rutin on gentamicin-induced ototoxicity in rats biochemically and histopathologically.