International Multidisciplinary Symposium on Drug Research and Development, Erzurum, Turkey, 5 October - 07 November 2017, pp.141, (Full Text)
Ilex paraguariensis A. St. Hil. (mate) is a South America plant and a member of Aquifoliaceae family. The medicinal parts of plant are dried or roasted leaves [1]. Two of the major components of mate are chlorogenic acid and ursolic acid that have anti-obesity and stimulator of lipolysis effects, respectively [2,3]. I. paraguariensis is presented in herbal slimming products due to its diuretic and lipolytic effects1. In the present study, new, simple and sensitive high performance liquid chromatography (HPLC) methods have been developed for qualitative and quantitative determination of ursolic acid and chlorogenic acid in eight herbal slimming products containing Ilex paraguariensis in Turkey. The developed methods can be used for routine quality control analysis of ursolic acid and chlorogenic acid in different herbal slimming products.