A novel determination of curcumin via Ru@Au nanoparticle decorated nitrogen and sulfur-functionalized reduced graphene oxide nanomaterials

Kotan G., KARDAŞ F., Yokus O. A., Akyildirim O., Saral H., Eren T., ...More

ANALYTICAL METHODS, vol.8, no.2, pp.401-408, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.1039/c5ay02950c
  • Journal Name: ANALYTICAL METHODS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.401-408
  • Erzincan Binali Yildirim University Affiliated: Yes

Abstract

We report the synthesis of Ru@Au nanoparticle involved L-cysteine functionalized reduced graphene oxide (rGO) composites (NSrGO/Ru@AuNPs). The nanocomposites were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD). The electrochemical determination of curcumin (CR) has been studied using square wave voltammetry (SWV) on a glassy carbon electrode (GCE) modified with NSrGO/Ru@AuNP composites (NSrGO/Ru@AuNPs/GCE). The effective surface areas (ESAs) of the rGO/GCE and NSrGO/Ru@AuNPs/GCE were calculated to be 347 cm(2) mg(-1) and 1289 cm(2) mg(-1), respectively. These results show that the electrochemical surface area of the NSrGO/Ru@AuNPs/GCE is 3.71 times higher than that of the rGO/GCE. The developed method was also applied successfully for the determination of CR in plasma and the linearity range of CR was 0.001-0.1 nM with a detection limit of 2.0 x 10(-13) M.