PREVALENCE AND DENSITY OF DEMODEX MITES (ACARI: DEMODECIDAE) IN PATIENTS WITH BRUCELLOSIS


Zeytun E.

Congress on Global Practice of Multidisciplinary Scientific Studies-XI, Munich, Almanya, 13 - 17 Ekim 2025, ss.822-830, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: Munich
  • Basıldığı Ülke: Almanya
  • Sayfa Sayıları: ss.822-830
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

This study was conducted to determine the prevalence and density of Demodex mites in patients diagnosed with brucellosis. A total of 79 patients with brucellosis (47 females, 32 males; mean age: 48.8 years) and 35 healthy controls (24 females, 11 males; mean age: 25.8 years) were included. Ethical approval was obtained from the Erzincan University Clinical Research Ethics Committee, and written informed consent was obtained from all participants. Biopsy samples were collected from the cheek, nasolabial, and chin regions using the standard superficial skin biopsy (SSSB) method, and were examined under a light microscope for the presence and count of Demodex mites. Biopsy samples containing ≥5 D. folliculorum and/or D. brevis were considered positive for Demodex. The mean Demodex count per cm² was calculated by dividing the total number of Demodex mites by the number of Demodex-positive participants. Data were analyzed using SPSS version 23.0 statistical software. A p-value of <0.005 was considered statistically significant. In this study, Demodex positivity was detected in 56 (70.9%) of the patients and in 5 (14.3%) of the controls. Among the patients, D. folliculorum was identified in 56 cases (mean: 86.57/cm²), while D. brevis was found in 2 cases (mean: 14.00/cm²). In contrast, among the 35 healthy controls, D. folliculorum was identified in 5 cases (mean: 6.20/cm²), and no D. brevis was detected. Comparison of patients and controls revealed that the differences in both prevalence and density of Demodex spp. were statistically significant (p < 0.005). In conclusion, similar to other patient groups, Demodex mites were found to be highly prevalent and abundant in individuals diagnosed with brucellosis.