Synthesis and bio-molecular study of (+)-N-Acetyl-a-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma


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Mustufa M. A., Ozen C., Hashmi I. A., Aslam A., Baig J. A., Yildiz G., ...More

BMC CANCER, vol.16, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16
  • Publication Date: 2016
  • Doi Number: 10.1186/s12885-016-2942-5
  • Journal Name: BMC CANCER
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Erzincan Binali Yildirim University Affiliated: Yes

Abstract

Background: The purpose of present work is to synthesize novel (+)-Dehydroabietylamine derivatives (DAAD) using N-acetyl-a-amino acid conjugates and determine its cytotoxic effects on hepatocellular carcinoma cells.