Synthesis and bio-molecular study of (+)-N-Acetyl-a-amino acid dehydroabietylamine derivative for the selective therapy of hepatocellular carcinoma


Mustufa M. A. , Ozen C., Hashmi I. A. , Aslam A., Baig J. A. , Yildiz G. , et al.

BMC CANCER, cilt.16, 2016 (SCI İndekslerine Giren Dergi)

Özet

Background: The purpose of present work is to synthesize novel (+)-Dehydroabietylamine derivatives (DAAD) using N-acetyl-a-amino acid conjugates and determine its cytotoxic effects on hepatocellular carcinoma cells.