A Novel Potentiometric PVC-membrane Cysteamine-Selective Electrode Based on Cysteamine-Phosphomolybdate Ion-Pair


Tumur M., Kanberoğlu G. S. , ÇOLDUR F.

CURRENT PHARMACEUTICAL ANALYSIS, cilt.16, ss.168-175, 2020 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 16 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1573412914666181017150529
  • Dergi Adı: CURRENT PHARMACEUTICAL ANALYSIS
  • Sayfa Sayıları: ss.168-175

Özet

Background: Cysteamine is used as an orphan drug in the treatment of cystinosis to prevent long-term cystine accumulation in lysosomes. Dosing in cysteamine treatment is extremely important and overdose may cause some side effects. Up to now, various analytical methods have been used for cysteamine determination. Many of these methods require sophisticated instniments, expert operators, time-consuming measurement procedures and manipulation steps, expensive supplies and long analysis time.