A Novel Potentiometric PVC-membrane Cysteamine-Selective Electrode Based on Cysteamine-Phosphomolybdate Ion-Pair

Tumur M., Kanberoğlu G. S., ÇOLDUR F.

CURRENT PHARMACEUTICAL ANALYSIS, cilt.16, sa.2, ss.168-175, 2020 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.2174/1573412914666181017150529
  • Dergi Adı: CURRENT PHARMACEUTICAL ANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
  • Sayfa Sayıları: ss.168-175
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

Background: Cysteamine is used as an orphan drug in the treatment of cystinosis to prevent long-term cystine accumulation in lysosomes. Dosing in cysteamine treatment is extremely important and overdose may cause some side effects. Up to now, various analytical methods have been used for cysteamine determination. Many of these methods require sophisticated instniments, expert operators, time-consuming measurement procedures and manipulation steps, expensive supplies and long analysis time.