Evaluation of Epithelial Cell Adhesion Molecule, Galectin‑3, and Proliferative Cell Nuclear Antigen Expression in Thyroid Papillary Carcinomas and Their Lymph Node Metastases

Daltaban F., Sayar İ., Tayfur M., Gürbüzel M., Balcı M. G.

NIGERIAN JOURNAL OF CLINICAL PRACTICE, cilt.29, ss.350-355, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29
  • Basım Tarihi: 2026
  • Doi Numarası: 10.4103/njcp.njcp_346_24
  • Dergi Adı: NIGERIAN JOURNAL OF CLINICAL PRACTICE
  • Derginin Tarandığı İndeksler: Scopus, Science Citation Index Expanded (SCI-EXPANDED), MEDLINE
  • Sayfa Sayıları: ss.350-355
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

Thyroid papillary carcinoma (PTC) is the most common carcinoma

of thyroid carcinomas and endocrine carcinomas. The diagnosis of thyroid PTC is

made mainly by the presence of nuclear features such as nuclear clearing, groove,

and nuclear inclusions. Some benign lesions of the thyroid may have nuclear

features and growth patterns of papillary thyroid carcinomas, which can make the

differential diagnosis difficult. Different immunohistochemical markers have always

been needed to reduce diagnostic errors and detect malignancies in routine practice.

As in all tumor cases, studies continue to understand carcinogenesis in thyroid

carcinomas. One of the ways that can help understand this involves the use of new

and effective immunohistochemical markers.