NIGERIAN JOURNAL OF CLINICAL PRACTICE, vol.29, pp.350-355, 2026 (SCI-Expanded, Scopus)
Thyroid papillary carcinoma (PTC) is the most common carcinoma
of thyroid carcinomas and endocrine carcinomas. The diagnosis of thyroid PTC is
made mainly by the presence of nuclear features such as nuclear clearing, groove,
and nuclear inclusions. Some benign lesions of the thyroid may have nuclear
features and growth patterns of papillary thyroid carcinomas, which can make the
differential diagnosis difficult. Different immunohistochemical markers have always
been needed to reduce diagnostic errors and detect malignancies in routine practice.
As in all tumor cases, studies continue to understand carcinogenesis in thyroid
carcinomas. One of the ways that can help understand this involves the use of new
and effective immunohistochemical markers.