In the present report, a new voltammetric sensor based on copper oxide nanoparticles involved in 2-(3-acetoxy4-methoxybenzylidenamino)-thiophenol (AMT) ionic liquid (CuO NPs/ILs) was developed for atrazine (ATR) analysis. Firstly, the CuO NPs/ILs modified surface was investigated by using transmission electron microscopy (TEM), X-ray diffraction (XRD), cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and energy dispersive X-ray analysis (EDX). The linearity range and the detection limit (LOD) of the prepared sensor were calculated as 1.0 x 10(-11)-2.0 x 10(-9) and 2.0 x 10(-12) M, respectively. Voltammetric sensor was also applied to wastewater samples with high recovery. (C) 2017 Elsevier B.V. All rights reserved.