7th Eurasia Biochemical Approaches & Technologies (EBAT), Antalya, Türkiye, 6 - 09 Kasım 2025, ss.63, (Özet Bildiri)
Multicomponent reactions have an important place among other synthesis methods due to their high yields, easy application, applicability to total syntheses with small molecular weights and the existence of extensive literature on this subject 1. Reactions that use more than two starting materials are called "multicomponent reactions" (MCRs). MCRs reactions have recently offered a new approach to the synthesis of large and complex reactions in practice 2. With these reactions, three or more starting compounds are combined in a single step to produce new possible biologically active products. As a result of the one-pot 4-component reaction in the presence of aliphatic and aromatic amines and aldehydes with dimethyl acetylenedicarboxylate and malononitrile using known methods in the literature 3, new heterocyclic molecules with good anticancer activity potential were synthesized.