ALTERED BLOOD AND AQUEOUS HUMOR LEVELS OF ASPROSIN, 4-HYDROXYNONENAL, AND 8-HYDROXY-DEOXYGUANOSINE IN PATIENTS WITH DIABETES MELLITUS AND CATARACT WITH AND WITHOUT DIABETIC RETINOPATHY

Oruc Y., Celik F., Ozgur G., Beyazyildiz E., UĞUR K., Yardim M., ...Daha Fazla

RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, cilt.40, sa.12, ss.2410-2416, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 12
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1097/iae.0000000000002776
  • Dergi Adı: RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.2410-2416
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Evet

Özet

Purpose: Diabetic retinopathy (DRP) is the formation of edema and small vessels in the retina due to high blood glucose levels. Asprosin is a hormone that stimulates the release of glucose from the liver into the circulation. Considering the relationship between oxidative stress and DRP, our study aimed to determine the levels of the oxidative stress markers 4-hydroxynonenal (4-HNE) and 8-hydroxy-2'-deoxyguanosine (8-OHdG), as well as asprosin, in the blood and aqueous humor (Aq) of patients with and without DRP.