The Effect of Anakinra on Paclitaxel-Induced Peripheral Neuropathic Pain in Rats
TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION, cilt.44, sa.6, ss.287-294, 2016 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44 Sayı: 6
- Basım Tarihi: 2016
- Doi Numarası: 10.5152/tjar.2016.02212
- Dergi Adı: TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.287-294
- Erzincan Binali Yıldırım Üniversitesi Adresli: Evet
Özet
Objective: Paclitaxel is used in the treatment of cancer, and it may cause interleukin-1 beta (IL-1 beta)-related peripheral neuropathic pain. While our primary aim was to investigate the analgesic efficacy of an IL-1 beta antagonist, a secondary outcome was to assess whether a correlation exists between analgesic effects and antioxidant activity.