Typha domingesis is a herbaceous plant growing around the swaps, lakes, and riverbeds. In this study, concentrations of heavy metals and mineral elements in root, stem, leaf, and sediment samples of T. domingensis were analyzed. Samples were collected from four different locations around Karasu River (Ulukoy, Bessaray, Saztepe, Kilimli) as one of the most important tributaries of the River Euphrates. Additionally, chlorophyll and carotenoid levels and lipid peroxidation features of the plant samples were investigated. Variations between the sampling locations and the correlation between the parts of plants were statistically evaluated. As revealed by the data, there were no significant differences between chlorophyll and carotenoid levels or lipid peroxidation in samples collected from different locations. Al showed the highest concentration in sediments, and K was the highest in samples obtained from different parts of the plants that were studied. It was observed that T. domingesis was acceptable as a good biomonitor plant for different metals.