Akademik Veri Yönetim Sistemi
2. BİLSEL INTERNATIONAL TRUVA SCIENTIFIC RESEARCHES AND INNOVATION CONGRESS 16-17 DECEMBER ÇANAKKALE / TURKEY, Çanakkale, Türkiye, 17 Aralık 2023
Thymus migricus is an endemic and highly biodiverse plant species belonging to the Lamiaceae family. This
plant is often found in mountainous areas, especially on limestone grounds. The species is adapted to arid and
semi-arid climates, especially in high mountain regions. Morphologically, T. migricus is generally recognized
by its small-sized, densely hairy leaves and characteristic essential oil glands. Studies on the biochemical
composition of T. migricus have highlighted the pharmacological potential of the plant. In particular, the leaves
and flowers of T.migricus have been identified as a rich source of antioxidants, polyphenols and essential oils.
These components may support the plant's antioxidant, anti-inflammatory, and antimicrobial properties. There
have been some reports of Thymus migricus being used in Van herbed cheese, tea, and for traditional medicinal
purposes in Eastern Turkey and Iran. In this study, Thymus migricus was collected from Erzincan Dumanlı
Nature Park. The aerial parts of plant material were freshly used for essential oil isolation. The fresh aerial
parts (400 g) were cut into small pieces and subjected to hydro distillation using a Neo-Clevenger-type
apparatus in 2-liter deionized water and maintained for 2 hours. The hydro distillation process was carried out in
triplicate. Decanted and dried over Na2SO4 essential oils were kept at +4 °C in sealed dark vials. The analysis
was performed using the Thermo Scientific GC-MS instrument. Total 38 components, representing 99.25% of
the total oils were identified. Main components of the oil were determined as carvacrol (46.91 %), thymol
(18.06 %), p-cymene (9.17%) and γ-terpinene (6.14%). Antimicrobial susceptibility tests were applied to 7
pathogenic bacterial strains with these extracts. Imipenem was used as a positive control. Inhibition zones was
measured as 35 mm for Pseudomonas aeruginosa, 18 mm for E.coli, 40 mm for Bacillus cereus, 41 mm for
Clostridium perfringens, 39 mm for Listeria monocytogenes, 35 mm for Staphylococcus aureus, and 28 mm for
Salmonella enteritidis. A strong antibacterial effect was observed in all 7 strains tested. Essentials oils of
Thymus migricus appears to have potential applications in the pharmacology and food industries.