One-Pot Synthesis of 1,2,3-Triols from Allylic Hydroperoxides and a Catalytic Amount of OsO4 in Aqueous Acetone


Alp C. , ATMACA U., ÇELİK M., GÜLTEKİN M. S.

SYNLETT, ss.2765-2768, 2009 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: Konu: 17
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1055/s-0029-1217965
  • Dergi Adı: SYNLETT
  • Sayfa Sayıları: ss.2765-2768

Özet

Allylic hydroperoxides were converted into the corresponding triols in the presence of a catalytic amount of OSO4. The present reaction involves regeneration of active osmium species by the hydroperoxide functionality and occurs in a diastereoselective manner to form triols in high yields. A plausible mechanism for the formation of 1,2,3-triols from allylic hydroperoxide is presented.