Anti-inflammatory effects of selective COX-2 inhibitors

SULEYMAN H., DEMIRCAN B., KARAGOZ Y., OZTASAN N., Suleyman B.

POLISH JOURNAL OF PHARMACOLOGY, cilt.56, sa.6, ss.775-780, 2004 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 56 Sayı: 6
  • Basım Tarihi: 2004
  • Dergi Adı: POLISH JOURNAL OF PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.775-780
  • Erzincan Binali Yıldırım Üniversitesi Adresli: Hayır

Özet

In this study, effects of rofecoxib, celecoxib, nimesulide on the acute phase of inflammation were studied in the carrageenan-induced paw edema model and their influence on the chronic phase of inflammation was evaluated in the cotton pellet granuloma tests. Additionally, effects of these drugs on capillary vascular permeability were examined in the hyaluronidase test and were compared with that of indomethacin (nonselective COX inhibitor).