Journal of Antivirals & Antiretrovirals, vol.13, no.S18, pp.1-4, 2021 (Peer-Reviewed Journal)
Background: It is necessary to use an effective vaccine to end the COVID-19 pandemic. CoronaVac vaccine is used
in our country and we aimed to examine the level of antibody development after the second dose.
Methods: This is a retrospective, cross-sectional research. The data of the people, who applied to a university hospital
between January and March 2021, were analyzed. Those who had SARS-CoV-2 IgG and IgM measurement in the
previous two weeks before the CoronoVac vaccine, and those who were both found negative and who had SARSCoV-2 IgG and IgM measurement after the second dose of CoronaVac vaccine were included in the research.
of spike protein specific IgG/IgM of SARS-CoV-2 in human serum with ELFA (Enzyme Linked Fluorescent Assay)
technique.
Results: 75 people were included in this research. It was found that the individuals had SARS-CoV-2 IgG and IgM
measurements between 14 and 21 days after the first dose of CoronaVac vaccine. It was observed that 12% (n=9) of
the cases had a history of COVID-19.The rate of positivity for SARS CoV-2 IgG level after vaccination was 100%.
Conclusions: It can be said that two doses of CoronaVac vaccine create an effective humoral immunity.
Keywords: COVID-19; CoronaVac vaccine; SARS-CoV-2 IgG